Draft 4/21/04


                                  

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 14A (Rule
(Rule 14a-101)
INFORMATION REQUIRED IN PROXY STATEMENT
SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES EXCHANGE ACT OF
Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934 (Amendment No.  )
Filed by the registrant [X] Registrantþ
Filed by a partyParty other than the registrant [ ] Registranto
Check the appropriate box: [ ] Preliminary proxy statement. [ ] Confidential, for use of the Commission only (as permitted by Rule 14a-6(e)(2)). [X] Definitive proxy statement. [ ] Definitive additional materials. [ ] Soliciting material under Section 240.14a-12 Third Wave Technologies, Inc. - -------------------------------------------------------------------------------- (Name
oPreliminary Proxy Statement
oConfidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
þDefinitive Proxy Statement
oDefinitive Additional Materials
oSoliciting Material Pursuant to §240.14a-12
THIRD WAVE TECHNOLOGIES, INC.
(Name of Registrant as Specified inIn Its Charter) - -------------------------------------------------------------------------------- (Name
(Name of Person(s) Filing Proxy Statement, if Other Thanother than the Registrant)
Payment of filing fee (checkFiling Fee (Check the appropriate box): [X] No fee required. [ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11. (1) Title of each class of securities to which transaction applies: - -------------------------------------------------------------------------------- (2) Aggregate number of securities to which transaction applies: - -------------------------------------------------------------------------------- (3) Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee is calculated and state how it was determined): - -------------------------------------------------------------------------------- (4) Proposed maximum aggregate value of transaction: - -------------------------------------------------------------------------------- (5) Total fee paid: - -------------------------------------------------------------------------------- [ ] Fee paid previously with preliminary materials. - -------------------------------------------------------------------------------- [ ] Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the form or schedule and the date of its filing. - -------------------------------------------------------------------------------- (1) Amount Previously Paid: - -------------------------------------------------------------------------------- (2) Form, Schedule or Registration Statement No.: - -------------------------------------------------------------------------------- (3) Filing Party: - -------------------------------------------------------------------------------- (4) Date Filed: - --------------------------------------------------------------------------------
þNo fee required.
oFee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.
(1)Title of each class of securities to which transaction applies:
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(2)Aggregate number of securities to which transaction applies:
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(3)Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee is calculated and state how it was determined):
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oFee paid previously with preliminary materials.
oCheck box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.
(1)Amount Previously Paid:
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(4)Date Filed:
N/A


THIRD WAVE TECHNOLOGIES, INC. --------------------- 2004
NOTICE OF 2007 ANNUAL MEETING OF SHAREHOLDERS TO BE HELD JUNE 22, 2004 --------------------- STOCKHOLDERS
to be held July 24, 2007
To our Shareholders: Stockholders:
NOTICE IS HEREBY GIVEN that the annual meeting of shareholdersstockholders of Third Wave Technologies, Inc., a Delaware corporation (the "Company"“Company”), will be held at the offices of the Company, 502 South Rosa Road,MG&E Innovation Center at 510 Charmany Drive, Madison, Wisconsin 53719 on June 22, 2004July 24, 2007, at 9:00 a.m., local time, for the following purposes: (1) To elect three directors each to serve for a term of three years expiring upon the 2007 annual meeting of shareholders or until their successors are elected and qualified; (2) To ratify the appointment of Ernst & Young LLP as the independent auditors of the Company for the year ending December 31, 2004; and (3) To transact any other business which is properly presented at the meeting.
• To elect two directors to serve for a term of three years expiring at the 2010 annual meeting of stockholders or until his successor is elected and qualified;
• To ratify the appointment of Grant Thornton LLP as the independent registered public accounting firm of the Company for the year ending December 31, 2007; and
• To transact any other business that is properly presented at the meeting.
The foregoing items of business are more fully described in the proxy statement accompanying this notice. Only shareholdersstockholders of record at the close of business on April 23, 2004May 25, 2007, are entitled to notice of and to vote at this meeting.
All shareholdersstockholders are invited to attend the meeting in person. However, to assure your representation at the meeting, you are urged to sign and return the enclosed proxy as promptly as possible in the postage prepaid envelope enclosed for that purpose. Any shareholderstockholder entitled to vote and attending the meeting may vote in person even if a proxy is returned.
By Order of the Board of Directors, /s/ JOHN COMERFORD John Comerford April 29, 2004
-s- KEVIN T. CONROY
Kevin T. Conroy
President and Chief Executive Officer
June 4, 2007


TABLE OF CONTENTS

PROXY STATEMENT
INFORMATION CONCERNING SOLICITATION AND VOTING
ELECTION OF DIRECTORS
Board of Directors and Committees
Compensation Committee Interlocks and Insider Participation
Director Compensation
RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
COMPENSATION COMMITTEE REPORT
EXECUTIVE COMPENSATION
Equity Compensation Plan Information
Executive Officers of the Company
REPORT OF THE AUDIT COMMITTEE
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS, DIRECTORS AND MANAGEMENT
SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
CODE OF BUSINESS CONDUCT
OTHER MATTERS


THIRD WAVE TECHNOLOGIES, INC. ---------------------
PROXY STATEMENT FOR THE 2004
2007 ANNUAL MEETING OF THE SHAREHOLDERS JUNE 22, 2004 --------------------- STOCKHOLDERS
INFORMATION CONCERNING SOLICITATION AND VOTING GENERAL
General
The enclosed proxy is solicited on behalf of Third Wave Technologies, Inc. (the "Company"“Company”, "us"“us”, "we"“we”, “our” or "our"“Third Wave”) for use at the annual meeting of shareholdersstockholders to be held on Tuesday, June 22, 2004July 24, 2007, at 9:00 a.m., local time, or at any adjournment or adjournments thereof, for the purposes set forth herein and in the accompanying notice of annual meeting of shareholders.stockholders. The annual meeting will be held at the principal executive offices of the CompanyMG&E Innovation Center at 502 South Rosa Road,510 Charmany Drive, Madison, Wisconsin 53719. The telephone number at that location is(608) 273-8933.
These proxy solicitation materials are being mailed on or about April 29, 2004June 4, 2007, to all shareholdersstockholders entitled to vote at the meeting. RECORD DATE Shareholders
Record Date
Stockholders of record at the close of business on April 23, 2004,May 25, 2007, the record date for the meeting, are entitled to notice of and to vote at the meeting. At the record date, 40,173,41142,221,561 shares of the Company'sCompany’s common stock were issued and outstanding. REVOCABILITY OF PROXIES
Revocability of Proxies
Any proxy given pursuant to this solicitation may be revoked by the person giving it at any time before its use by delivering to the Company a duly executed proxy bearing a later date, by attending the shareholderstockholder meeting and voting in person, or by delivering to the Secretary of the Company, at the Company'sCompany’s principal executive offices, 502 S. Rosa Road, Madison, Wisconsin 53719, a written notice of revocation. VOTING AND SOLICITATION
Voting and Solicitation
Each shareholderstockholder is entitled to one vote for each share held as of the record date for the meeting. Shareholders will not be entitled to cumulate their votes in the election of directors.
The cost of soliciting proxies will be borne by the Company. The Company expectsWe expect to reimburse brokerage firms and other persons representing beneficial owners of shares for their expenses in forwarding solicitation material to such beneficial owners. Proxies may also be solicited by certain of the Company'sour directors, officers and employees, without additional compensation, personally or by telephone, telegram,e-mail, facsimile or other means of communication. We have engaged Georgeson & Co. to assist us
Quorum; Abstentions; Broker Non-Votes
The presence, either in distributing materials, for a fee estimated at $5,000, plus reimbursement of out-of-pocket expenses. QUORUM; ABSTENTIONS; BROKER NON-VOTES Votes castperson or by proxy, or in personof the holders of a majority of the total outstanding shares of common stock as of the record date will constitute a quorum at the annual meeting. Abstaining votes and broker non-votes are counted for purposes of establishing a quorum. A broker non-vote occurs when a nominee holding shares for a beneficial owner does not vote on a particular matter because the nominee has not received instructions from the beneficial owner and does not have discretionary voting power for that particular item.
In the election of directors, the two director nominees receiving the most affirmative votes of the shares of common stock present or represented and entitled to vote at the meeting will be tabulated by the inspectorelected as directors. The affirmative vote of elections appointed for the meeting and will determine whether a quorum is present. We need a majority of the shares of common stock issuedpresent or represented and outstanding onentitled to vote is required to ratify the record date present,selection of Grant Thornton LLP as the independent public accounting firm to audit the financial statements of the Company.
An abstaining vote in person or by proxy, to have a quorum to allow us to hold the annual meeting. Shares that are voted "For", "Against" or "Abstain" with respect to any matter are treated as being present at the meeting. In the election of directors you can withhold youris not counted and therefore has no effect on the election. However, an abstaining vote foron all other proposals will have the same effect as a negative vote on the proposal. A


broker non-vote on any nominee. Withheld votes will be excluded entirely from the vote onproposal, including the election of directors, and will have no effect on the outcome. On the ratification of the appointment of Ernst & Young LLP, you can vote to "abstain". If you vote to "abstain", your vote will have the effect of a vote against the ratification. If you hold shares through a broker, follow the voting instructions you receive from your broker. If you do not submit voting instructions with respect to a matter and your broker does not vote your shares on that matter (so-called "broker non-votes"), your shares will not be countedincluded in determiningthe tabulation of the voting results and therefore does not affect the outcome of the vote on that matter. vote.
Any proxy that is returned using the form of proxy enclosed and whichthat is not marked as to a particular item will be voted for the election of the three nominees named in this proxy statement, for the ratification of the appointment of the independent auditors, as the case may be, with respect to the items not marked, and as the proxy holders deem advisable on other matters that may come before the meeting, as the case may be, with respect to the items not marked. DEADLINE FOR RECEIPT OF SHAREHOLDER PROPOSALSmeeting.
Deadline for Receipt of Stockholder Proposals of shareholders that are
To have a proposal intended to be presented by those shareholders at the Company's annual meetingAnnual Meeting of Stockholders to be held in 20052008 be considered for inclusion in the Company’s proxy statement and form of proxy relating to that meeting, a stockholder must be submitteddeliver written notice of such proposal in writing to the Secretary of the Company no later than February 5, 2008.
In addition, the bylaws provide that if a stockholder desires to submit a proposal for consideration at the Company's executive offices and received2008 Annual Meeting of Stockholders, or to nominate persons for election as director at that meeting, or both, the stockholder must deliver written notice of such proposal or nomination in writing in the form specified by the bylaws to the Secretary of the Company no later than December 31, 2004 in order that those proposals mayFebruary 5, 2008 or such proposal will be considered for possible inclusionuntimely. The bylaws further provide that the presiding officer of the meeting shall refuse to acknowledge any untimely proposal or nomination. Additionally, under applicable Securities and Exchange Commission rules the persons named in the proxy statement relating to that meeting. In addition,and form of proxy for the by-laws2008 Annual Meeting of the Company provide that any shareholder entitledStockholders would have discretionary authority to vote may nominate persons for election as directors or propose business to be brought before a meeting, or both, only if the shareholder has given timely notice in proper written form of the shareholder's intent to make aon any such untimely nomination or propose business. To be timely, the shareholder's notice must be delivered to or mailed and received at the principal executive offices of the Company not less than 120 days in advance of the first anniversary date of mailing of the Company's proxy statement released to shareholders in connection with the previous year's annual meeting of shareholders, unless no annual meeting was held in the previous year or the date of the annual meeting has been changed by more than 30 days from the date contemplated at the time of the previous year's proxy statement, in which case, to be timely such notice must be so received a reasonable time before the solicitation is made. The by-laws contain provisions regarding information that must be set forth in the shareholder's notice in order for it to be in proper form. PROPOSAL NO. 1 proposal.
ELECTION OF DIRECTORS
The Company'sCompany’s board of directors currently consists of ten persons,seven members and is divided into three classes serving terms of three years. ShareholdersOf the seven directors, all but Mr. Conroy are “independent” as such term is defined in the listing standards of The Nasdaq Stock Market. Stockholders elect one class of directors at each annual meeting. ThreeTwo directors are to be elected at this annual meeting each to hold office until the 20072010 annual meeting of shareholdersstockholders or until a successor has been duly elected and qualified. The other classesboard of directors will be elected at the Company's annual meetings of shareholders to be held in 2005has nominated Kevin Conroy and 2006. David Thompson for re-election as directors.
If any of the nomineesa nominee for director at the annual meeting becomes unavailable or declines to serve as a director at the time of the annual meeting, the proxy holders will vote the proxies in their discretion for any nominee who is designated by the current board of directors to fill the vacancy. We do notMr. Conroy and Mr. Thompson each have indicated their continued willingness and desire to serve as directors and we have no reason to expect any of the nomineesthat either nominee will be unable to be unavailable to serve. serve as a director if so elected.
The names of the three nominees for election to the board of directors at the annual meeting, and the other members of the board of directors, their ages as of the record date for the meeting, and certain information about them are set forth below. The names of the current directors with unexpired terms, their ages as of the record date, and certain information about them are also stated below. 2 NOMINEES FOR ELECTION AT THE ANNUAL MEETING FOR TERMS ENDING IN
Directors - Terms Ending in 2007
NAME AGE PRINCIPAL OCCUPATION - ---- --- -------------------- Lance Fors, Ph.D.......................... 46 Chairman of the Board
Name
Age
Principal Occupation
Kevin T. Conroy41President and Chief Executive Officer, Third Wave Technologies, Inc.
David A. Thompson(3)...................... 62 Thompson(1)(3)65Retired; Former Senior Vice President & President, Diagnostic Division, Abbott Laboratories John J. Puisis............................ 44


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Directors - Terms Ending in 2008
Name
Age
Principal Occupation
James Connelly(2)(4)60Partner, Foley & Lardner
Lionel Sterling(2)(3)69President, and Chief Operating Officer, Third Wave Technologies,Equity Resources, Inc.
DIRECTORS CONTINUING IN OFFICE
Directors - TERMS ENDING IN 2005 Terms Ending in 2009
NAME AGE PRINCIPAL OCCUPATION - ---- --- -------------------- Tom Daniel(1)(2)(3)....................... 39 General Partner, Schroder Ventures Life Sciences G. Steven Burrill(2)...................... 59 Chief Executive Officer, Burrill & Company Lloyd M. Smith, Ph.D.(1)(3)............... 49 John D. MacArthur Professor of Chemistry, University of Wisconsin, Director of the Genome Center at the University of Wisconsin, Madison and Member, Advisory Board, Third Wave Technologies, Inc.
DIRECTORS CONTINUING IN OFFICE - TERMS ENDING IN 2006
NAME AGE PRINCIPAL OCCUPATION - ---- --- -------------------- John Neis(1)(2)(3)........................ 48 Senior Partner, Venture Investors LLC Sam Eletr, Ph.D........................... 65 Retired; Former Chairman and CEO of Applied Biosystems
Name
Age
Principal Occupation
Gordon F. Brunner......................... 65 Partner, Living Longer Proactive Health; retiredBrunner(1)(3)(4)68Retired; Former Senior Vice President, Chief Technology Officer, and member of the Boardboard of Directorsdirectors of Procter & Gamble Co. Company; Partner, Cincinnati Living Longer ProActive Health Center
Lawrence Murphy(1)(2)64Independent Business Consultant, former executive vice president and secretary of Core Industries, Inc.
Katherine Napier(4)52Consultant, former senior vice president of marketing of McDonald’s Corp.
- --------------- (1) Member of the compensation committee (2) Member of the audit committee (3) Member of the nominating committee The nominating committee unanimously recommended to the board of directors that Mr. McGuire, whose term as a member of the board of directors expires at the annual meeting of shareholders, not be nominated
(1)Member of the compensation committee
(2)Member of the audit committee
(3)Member of the nominating and governance committee
(4)Member of the innovation and technology committee
Nominees for an additional term. The board of directors unanimously adopted the nominating committee's recommendation. There are no family relationships among any of the directors or executive officers of the Company. NOMINEES FOR ELECTION AT THE ANNUAL MEETING FOR TERMS ENDING IN 2007 Lance Fors, Ph.D., our founder and Chairman of the Board, Election for Terms Ending in 2010
Kevin T. Conroyhas served as our President and Chief Executive Officer and as one of our directors since our inceptionDecember 2005. Mr. Conroy joined Third Wave as Vice President of Legal Affairs in 1993. Dr. ForsJuly 2004 and served as our PresidentGeneral Counsel from 1993 until 2003. Dr. Fors receivedOctober 2004 to December 2005. Prior to joining Third Wave, Mr. Conroy worked for GE Healthcare, where he oversaw the development and management of its information technologies group intellectual property portfolio, and developed and executed litigation, licensing, and corporate product acquisition legal strategies. Before joining GE, Mr. Conroy was Chief Operating Officer of two early stage venture-based technology companies in Northern California. Prior to those positions, he was an intellectual property litigator at two Chicago law firms, McDermott Will & Emery, and Pattishall, McAuliffe, Newbury, Hilliard and Geraldson, where he was a partner. He earned his Ph.D.B.S. in molecular biologyelectrical engineering at Michigan State University and his J.D. from the California InstituteUniversity of Technology in 1990. Dr. Fors has over twenty years of research and development experience and is the inventor on 21 issued and pending patents in the area of DNA and RNA sequence analysis. Michigan.
David A. Thompson, Chairman and Lead Independent Director, has served as one of our directors since August 1997.1997 and as Chairman and Lead Independent Director since 2005. Mr. Thompson retired from Abbott Laboratories in 1995, where he worked for overmore than 30 years. He held several corporate officer positions 3 with Abbott Laboratories, including: Senior Vice President & President DiagnosticDivision 1983-1995, Vice President Human Resources1982-1983, Vice President Corporate Materials Management1981-1982 and Vice President Operations1974-1981. Mr. Thompson currently serves on the board of directors of St. Jude Medical Inc., a medical device company. John J. Puisis has served as our Senior Vice President since September 2001. Mr. Puisis also served as our Chief Financial Officer from September 2001 until October 2003. In January 2003, Mr. Puisis was also assigned the title and duties of Chief Operating Officer and in October of 2003, he was assigned the title and duties of President. Mr. Puisis was appointed to our board of directors in February 2004. From 1996 until he joined the Company, Mr. Puisis held senior management positions at the Spencer Stuart and Egon Zehnder executive recruitment firms, specializing in recruiting for the biotechnology and pharmaceutical industries. From 1989 to 1996, Mr. Puisis held key financial executive positions at DEKALB Genetics and Kraft Foods. Prior to 1989, Mr. Puisis held various positions at several large public accounting firms. Mr. Puisis received an M.B.A. from Northwestern University and a B.A. in accounting from Northern Illinois University. He is a certified public accountant.
THE COMPANY'SCOMPANY’S BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDS A VOTE "FOR"“FOR” THE NOMINEES SET FORTH ABOVE. DIRECTORS WHOSE TERMS EXTEND BEYOND THE ANNUAL MEETING Tom Daniel NOMINEES.
Directors Whose Terms Extend Beyond the Annual Meeting
Gordon F. Brunnerhas served as one of our directors since October 1999. He is General Partner with Schroder Ventures Life Sciences, a venture capital investment firm, where he has focused on life science investments in the United States and Europe since 1998. From 1995 to 1998, Mr. Daniel was an associate with Domain Associates, a United States venture capital firm focused on the life sciences. Before Domain, Mr. Daniel worked for Charles River Ventures, a United States venture capital firm focused on biotechnology investments. Mr. Daniel is a director of Oxagen and Solexa and is responsible for investments in Cellzome, Sunesis and a number of other private and public companies. Mr. Daniel received an M.B.A. from Harvard Business School, was a member of a genetics research team at the University of North Carolina, Chapel Hill from 1983-1984, and received an M.A. in Biological Sciences from Oxford University. G. Steven Burrill has served as one of our directors since October 1998. Mr. Burrill is Chief Executive Officer of Burrill & Company, a Life Sciences Private Merchant Bank which he founded in 1994. Prior to founding Burrill & Company, Mr. Burrill was a partner of Ernst & Young from 1977 through 1993. Mr. Burrill is a director of Catalyst Biosciences, DepoMed (DEPO), Galapagos Genomics, and Targacept. He currently serves as Board Chairman for Paradigm Genetics (PDGM) and Pyxis Genomics. Mr. Burrill received a B.B.A. from the University of Wisconsin, Madison. Lloyd M. Smith, Ph.D., has served as one of our directors since our formation and also serves on our scientific advisory board. Dr. Smith is John D. MacArthur Professor of Chemistry and Director of the Genome Center at the University of Wisconsin, Madison. Dr. Smith was the primary inventor of automated DNA sequence analysis. Dr. Smith regularly consults and advises us in our research and development efforts. He is chair of the scientific advisory boards of ProCognia Ltd. and GenTel Corporation and a member of the scientific advisory board of Curagen Corporation. John Neis has served as one of our directors since August 1994. Mr. Neis is Senior Partner of Venture Investors LLC, a firm that is the manager and general partner of Madison, Wisconsin-based venture capital management funds. He also serves on the Advisory Board of the Weinert Applied Ventures Program at the University of Wisconsin. Mr. Neis received a B.S. in finance from the University of Utah and an M.S. in business from the University of Wisconsin, and is a Chartered Financial Analyst. Gordon F. Brunner has served as one of our directors since January 2003. Mr. Brunner is currently a partner with Living Longer Proactive Health and was senior vice president, chief technology officer, head of worldwide research and development, andserved as Chief Technology Officer as well as a member of the board of directors of the Procter & Gamble Co.Company, until his retirement after 40 years of service. He has more than 40 years'extensive experience leveraging innovative technology platforms to the pharmaceutical, 4 over-the-counter and consumer markets. He received a B.S. degree in biochemical engineering from the University of Wisconsin-Madison and an M.B.A. degree from Xavier University. Sam Eletr, Ph.D.Mr. Brunner is a partner in the Cincinnati Living Longer ProActive Health Center and serves as a director of one other public company, Scotts Miracle-Gro


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Corporation, as well as privately-held Iams Imaging and Beverage Holdings, LLC. He also serves on the boards for Christ Hospital (Cincinnati, Ohio), the Wisconsin Alumni Research Foundation and Xavier University.
James Connellyhas served as onea director since July 2005. Mr. Connelly is a partner in the Foley & Lardner law firm, where he served as founding chairman of our directorsthe health law practice. He brings to Third Wave more than 25 years of experience providing strategic business and legal advice to large health care networks, clinics and laboratories. He also has advised a number of emerging biotechnology and life sciences companies. Mr. Connelly earned his bachelor’s degree from Marquette University and his law degree from the Georgetown University Law Center. He has served as a director and chairman of the board of numerous privately-held businesses and currently serves on the board of trustees of Ripon College.
Lawrence Murphyhas served as a director since January 2006. Mr. Murphy, an independent business consultant, brings to Third Wave’s board more than 30 years of business experience in strategic partnerships, mergers and acquisitions, operations, finance, law and administration. He has served as the lead business advisor on significant transactions. Mr. Murphy served as executive vice president and secretary of Core Industries, Inc., a publicly-held (NYSE) diversified manufacturer, from 1981 until its sale in 1997. He was a practicing attorney and certified public accountant before joining Core Industries. He received a B.S. degree in accounting from the University of Detroit Mercy and a J.D., cum laude, from Wayne State University Law School. Mr. Murphy serves as a director of Jabil Circuit, Inc., a publicly-held (NYSE) global electronics manufacturing service company with more than $10 billion in revenue.
Katherine Napierhas served as a director since June 2002. Dr. Eletr co-founded Applied Biosystems, Inc.2006. Ms. Napier is a20-year veteran of Procter & Gamble, where from 1979 to 2002 she rose from assistant brand manager to vice president and general manager of the company’s North American pharmaceutical division, which experienced unprecedented growth during her five year tenure, including the launch of Actonel, the company’s fastest growing brand ever to $1 billion. Most recently, Ms. Napier served as senior vice president of marketing at McDonald’s Corporation where she led the development and execution of that company’s strategy to reinvigorate its Chairmanbusiness with women and Chief Executive Officer until 1987. Prior to founding Applied Biosystems, Dr. Eletr managedfamilies. She received her B.A. in economics and Studio Fine Arts from Georgetown University and an M.B.A. in marketing and finance from Xavier University. Ms. Napier also serves on the analyticalboard of the Alberto Culver Company and medical instruments group at Hewlett-Packard Co.'s corporate research laboratories. Dr. Eletr most recentlyMentor Corporation, Catholic Health Care Partners, Xavier University, and the board of visitors of Wake Forest University Calloway School of Business.
Lionel Sterlinghas served as a director since August 2004. Mr. Sterling is president of Equity Resources, Inc., a private investment firm. He previously co-founded and served as chairman and chief executive officer of Lynx Therapeutics Inc., a publicly traded genomics company. He received an M.A. in physics and a Ph.D. in biophysical chemistry, both at the University of California-Berkeley. VOTE REQUIRED Directors are elected by a pluralitymanaging partner of the votes cast. Shares represented by executed proxies will be voted, if authority to do so is not withheld, forprivate investment firm Whitehead/Sterling. He serves on the electionboard of Molecular Insight Corporation. He also has served as chairman of the three nominees. Votes withheldboard of directors of Rayovac Corporation, Executive Vice President and Director of United Brands Company, and Sector Executive and Chief Financial Officer of American Can Company. He also held various investment and financial positions at Donaldson, Lufkin & Jenrette Inc. and ITT Corporation. Mr. Sterling holds an M.B.A. from any director will have no effect on the outcome. BOARD MEETINGS, COMMITTEES AND DIRECTOR COMPENSATION New York University.
Board of Directors and Committees
The board of directors provides oversight with respect to the Company'sCompany’s strategic direction and significant corporate policies. Of the ten directors, all but Dr. Fors and Mr. Puisis are "independent" as such term is defined in the listing standards of the National Association of Securities Dealers. The board of directors has adopted Corporate Governance Guidelines which are available at the Company's website twt.com. The board of directors has threefour standing committees: a compensation committee, an audit committee, and a nominating and governance committee, and an innovation and technology committee. From time to time, the board has created various ad hoc committees for special purposes.
The board of directors held a total of six meetingsmet 4 times during 20032006 and all directors attended at least 75% of the total number of meetings of the board and committees of the board on which the director served during 2003.2006. The board held a total of 2 executive sessions during 2006. The Company encourages but does not require its directors to attend the annual meeting of stockholders. Two directors attended the shareholders. Shareholders2006 annual meeting of stockholders. Beginning with the 2007 annual meeting of stockholders, we moved the date of the annual meeting to coincide with a board of directors meeting, in part, so that all directors would be in Madison at the time of the annual meeting.


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Stockholders may communicate withcontact our board of directors, either as a whole or with an individual member,director, or a specified board committee or group, by writing to them at the following address:
c/o Corporate Secretary
Third Wave Technologies
502 S. Rosa Road
Madison, WI 53719
The Corporate Secretary will have discretion to determine whether a communication is proper for submission to the intended recipient. Communications that raise personal grievances, are solicitations, do not relate to the Company or that are frivolous are presumptively inappropriate for delivery. For further detail on the procedures set forth onfor contacting our website twt.com. COMPENSATION COMMITTEE The compensation committee consists of Messrs. Smith, Neis and Daniel. The board of directors, has determined that eachplease visit the corporate governance section of our websitewww.twt.com.
Compensation Committee
Gordon Brunner (chair), Lawrence Murphy and David Thompson currently serve on the compensation committee. Each member of the compensation committee is "independent"“independent” as such term is defined in the listing standards of the National Association of Securities Dealers.The Nasdaq Stock Market. The compensation committee makes recommendations to the board of directors regarding our employee benefit plans and the compensation of officers.met 6 times during 2006. The compensation committee heldoperates under a total of five meetings during 2003. The board of directors has adopted a compensation committee charter,Compensation Committee Charter, which is available at the Company'sCompany’s website twt.com. AUDIT COMMITTEE www.twt.com.
The compensation committee’s responsibilities, which are discussed in detail in its charter, include, among other duties, the responsibility to:
• Establish our executive compensation philosophy, oversee our processes and procedures for consideration and determination of executive and director compensation and review and approve all executive compensation and submit it to the board for its information;
• Review and evaluate, without the CEO present, the annual report from the nominating and governance committee with respect to the CEO’s performance relative to our goals and objectives, establish the individual elements of the CEO’s total compensation based on this evaluation and review and approve CEO compensation;
• Administer and implement our incentive compensation plans and equity-based plans, and any material amendments to such plans;
• Advise on the setting of compensation for officers whose compensation is not subject to compensation committee approval;
• Review and approve, for the CEO and our other executive officers, when and if appropriate, employment agreements, severance agreements and change in control provisions or agreements; and
• Evaluate and recommend to the entire board of directors appropriate compensation for our directors.
The agenda for meetings of the compensation committee is determined by its chairman with the assistance of our vice president of finance and operations. Meetings of the compensation committee are regularly attended by our CEO and our vice president of finance and operations. Our CEO annually reviews the performance of each of our other executive officers and, based on such review, makes compensation recommendations to the compensation committee, including recommendations for salary adjustments, annual cash incentives, and long-term equity-based incentives. As noted above, our directors’ compensation is determined by our board of directors after receiving the recommendation of the compensation committee.
The committee has used compensation consultants in past years to assist in developing compensation policies and practices. During 2006, the Committee utilized the services of Lander Brown, former Vice President Human Resources and Administration, in a consulting capacity and also engaged Hewitt Associates to assist it in reviewing and analyzing the Company’s long-term incentive compensation programs. In the future, the Committee may engage or seek the advice of compensation consultants. In addition, the committee may form, and delegate authority to, subcommittees when it deems appropriate.


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Audit Committee
The audit committee appointsrecommends to the board the appointment of our independent auditors, directs the scope of the audit of our financial statements and other services provided by our independent auditors, reviews the accounting principles and procedures to be used for financial statements and reviews the results of the audit. The audit committee also is also responsible for the pre-approval of all services provided by our independent auditors. The
James Connelly, Lawrence Murphy and Lionel Sterling (chair) currently serve on the audit committee. Each member of the audit committee consists of Messrs. Neis, Burrill and Daniel. The board of directors has determined that each member is "independent"“independent” as such term is defined in the listing standards of the National Association of Securities Dealers. The board of directors has also determined that G. Steven Burrill isNasdaq Stock Market. Mr. Sterling and Mr. Murphy are each considered an audit“audit committee financial expertexpert” as such term is defined by the rules of the Securities and Exchange Commission.Commission in Item 407(d)(5) ofRegulation S-K. The board of directors has adoptedaudit committee operates under an Audit Committee Charter, which is available at the Company'sCompany’s website twt.com. 5 www.twt.com.  Information regarding the functions performed by the audit committee and the number of meetings held during 20032006 is set forth in the "Report“Report of the Audit Committee",Committee,” included in this proxy statement. NOMINATING COMMITTEE
Nominating and Governance Committee
The nominating and governance committee evaluates and recommends candidates for election or appointment to the board of directors. The nominating and governance committee has not established any specific minimum qualifications that any candidate for director must meet, but considers a wide array of factors, including the candidate'scandidate’s knowledge of our industry, the candidate'scandidate’s educational and professional experience as well the candidate'scandidate’s reputation. The board of directors has adoptednominating and governance committee met 8 times in 2006. The nominating and governance committee operates under a Nominating and Governance Committee Charter, which is available at the Company'sCompany’s website twt.com. Thewww.twt.com.
Gordon Brunner, Lionel Sterling and David Thompson (chair) currently serve on the nominating committee consists of Messrs. Daniel, Neis, Smith and Thompson. The board of directors has determined that eachgovernance committee. Each member of the nominating and governance committee is "independent"“independent” as such term is defined in the listing standards of the National Association of Securities Dealers. The Nasdaq Stock Market.
The nominating and governance committee will consider director candidates recommended by shareholders.stockholders. Recommendations may be sent to John Comerford, Vice President, General Counsel andCindy Ahn, Corporate Secretary, 502 South Rosa Road, Madison, Wisconsin 53719. Any recommendation submitted by a shareholderstockholder must include the name and address of the shareholder,stockholder, any arrangements between the shareholderstockholder and the candidate pursuant to which the candidate is being nominated, and any information that would be required under the rules of the Securities and Exchange Commission to be included in the Proxy Statementproxy statement had the candidate been nominated by the board of directors. The nominating and governance committee will apply the same standards in considering candidates submitted by shareholdersstockholders as it applies to other candidates. COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
Innovation and Technology Committee
The innovation and technology committee assists the board in providing counsel to the Company’s senior management on strategic management of basic technology, innovation, medical affairs, and regulatory issues including the portfolio of development projects, management and tracking systems for critical projects, technology development and acquisition plans, and technical personnel development. The committee also assists the board and the company in interfacing with appropriate advisory and thought leader interactions.
Gordon Brunner (chair), James Connelly and Katherine Napier currently serve on the innovation and technology committee.
Compensation Committee Interlocks and Insider Participation
None of the members of the compensation committee is currently, or has ever been at any time since our formation, an officer or employee of the Company or any of its subsidiaries. No memberNone of the compensation committeeour executive officers serves as a member of the board of directors or compensation committee of any entity that has one or more officers serving as a member of our board of directors or compensation committee. DIRECTOR COMPENSATION Upon initial election, our non-employee directors receive a stock option grant of 30,000 options. The price of these options is determined by the fair market value of the Company stock on the date of grant. Following the third year of initial election, our non-employee directors receive an annual grant of 10,000 options. Options vest at 25% per year on the anniversary date of the option grant and accelerate upon a change of control of the Company consistent with the terms outlined in the Company's stock option grant agreements.


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Director Compensation
Our non-employee directors receive an annual retainer of $12,000,$40,000, a board meeting fee of $1,500 for regularly scheduled board meetings physically attended and a board$500 for each meeting attended by teleconference. Committee chairs receive an additional annual retainer of $7,500 and directors who hold committee meeting participation feepositions receive an additional annual retainer of $500$5,000 for each committee participation. Our chairman and lead independent director, Mr. Thompson, receives an additional $15,000 per meeting.year for serving in such position. Our directors are reimbursed for allreasonable director-related expenses incurred as a result of providing service to the Company or at the Company's request PROPOSAL NO.Company’s request.
Our2006-2007 stock option program for non-employee directors is as follows:
• new directors receive an initial grant of 45,000 options on the date they are first elected or appointed to the board of directors, which options vest in annual 15,000 share increments over three years;
• in year four of a director’s tenure, and each year thereafter during his or her tenure, such director receives an additional grant of 15,000 options, which options vest in full after one year;
• effective beginning with the 2007 annual meeting of stockholders, annual option grants are made on the date of the Company’s annual stockholders’ meeting (instead of on the directors’ anniversary dates);
• in the first year a director is entitled to receive an annual option grant on the annual meeting date, if such director’s anniversary date falls before the annual meeting date in that year, the director receives an annual option grant on his or her anniversary date, reduced on a proportionate basis to reflect the percentage of one year existing between such anniversary date and the annual meeting date;
• effective beginning in 2007, the initial option grant for a new director is made on the date that the director is first elected or appointed to the board of directors, but adjusted on a proportionate basis relative to the date of the annual stockholders’ meeting for the year of the grant if the date that the director is elected or appointed to the board of directors is a date other than the date of the annual stockholders’ meeting, with vesting tied to the date of the annual stockholders’ meeting for that year; and
• all director options vest in full upon a change of control.
In April 2007, we adopted a program under which directors will have the option of accepting shares of the Company’s common stock in lieu of cash compensation.
2006 Non-Employee Director Compensation Table
The following table sets forth information concerning the compensation paid or accrued during 2006 to the non-employee directors of the Company:
             
  Fees Earned
  Option
    
  or Paid in
  Awards
    
Name
 Cash($)  ($)(1)  Total ($) 
 
Gordon Brunner  66,500   43,107   109,607 
James Connelly  57,500   34,835   92,335 
Lawrence Murphy  56,000   28,240   84,240 
Katherine Napier  27,000   12,009   39,009 
John Neis  28,000   2,241   30,241 
Lionel Sterling  57,500   29,678   87,178 
David Thompson  75,000   45,316   120,316 
(1)The amounts shown in this column indicate the dollar amount of compensation cost recognized by us for financial statement reporting purposes in 2006 pursuant to FAS 123R for director stock option awards granted in 2006 and in prior years. Pursuant to Securities and Exchange Commission (“SEC”) rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting conditions. For additional information regarding the assumptions made in calculating these amounts, see Note 2 to the consolidated


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financial statements included in our Annual Report on Form10-K for the year ended December 31, 2006. These amounts reflect the Company’s accounting expense for these awards, and do not correspond to the actual value that will be recognized by the directors.
(2)For each director, the full grant date fair value for options awarded in 2006 computed in accordance with FAS 123R and the aggregate number of option awards outstanding at December 31, 2006 was as follows:
         
     Outstanding
 
  Grant Date
  Option
 
  Fair Value of
  Awards at
 
  Option
  Fiscal Year
 
  Awards ($)  End 
 
Gordon Brunner  27,500   45,000 
James Connelly  16,100   40,000 
Lawrence Murphy  86,850   45,000 
Katherine Napier  82,350   45,000 
John Neis  19,900    
Lionel Sterling  37,950   45,000 
David Thompson  57,400   131,800 
Generally, the full grant date fair value is the amount that we would expense in our financial statements over the award’s vesting schedule. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting conditions. For additional information regarding the assumptions made in calculating these amounts, see Note 2 to the consolidated financial statements included in our Annual Report onForm 10-K for the year ended December 31, 2006.
RATIFICATION OF APPOINTMENT OF AUDITORS INDEPENDENT REGISTERED
PUBLIC ACCOUNTING FIRM
The audit committee and the board of directors has appointed Ernst & YoungGrant Thornton LLP as the independent auditorsregistered public accounting firm of the Company for the current fiscal year ending December 31, 2004. Ernst & Young2007.
Fees Paid or Due to Grant Thornton LLP has audited the Company's financial statements since its inception. 6 FEES PAID OR DUE TO ERNST & YOUNG LLP In addition to retaining Ernst & Young LLP to audit our financial statements, we engage it from time to time to perform other services.
The table below shows the total fees billed by Ernst & YoungGrant Thornton LLP for its services in 20022006 and 2003. 2005.
         
  2006  2005 
 
Audit Fees(1) $200,200  $194,225 
Audit-Related Fees(2)  70,323   13,896 
Tax Fees(3)  21,797   8,256 
All Other Fees      
         
Total $292,320  $216,377 
         
FEE TYPE FISCAL 2002 FISCAL 2003 - -------- ----------- -----------
(1)Audit Fees*................................................. $261,500 $189,650 Audit Related Fees.......................................... $ 15,145 $ 1,500 Fees consist of the aggregate fees billed for professional services rendered for the audit of the Company’s annual financial statements and reviews of the financial statements included in the Company’s Quarterly Reports onForm 10-Q and services that are normally provided by the independent public accounting firm in connection with statutory and regulatory filings or engagements. These fees include fees billed for review and evaluation of the Company’s internal control over financial reporting and attest services relating thereto.
(2)Audit-related fees consisted of the aggregate fees billed for assurance and related services that are reasonably related to the performance of the audit or review of the Company’s consolidated financial statements and are not reported under “Audit Fees.”
(3)Tax Fees**.................................................. $ 64,475 $ 40,450 All Other Fees.............................................. 0 0 -------- -------- Total....................................................... $341,120 $231,600 ======== ======== fees principally included review of and consultation regarding the Company’s federal, state and foreign tax returns and tax planning.
- --------------- * Audit related services include quarterly and year-end reviews to discuss operating results, current business and accounting issues. The auditors have also issued a letter to management detailing observations made during the course of the audit and did meet with the Audit Committee in advance and upon completion of the audit. ** Tax related services included work related to the filing of the Company tax return for 2002, tax estimates and extension filings, and consultation with management representatives on state tax related matters.


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The audit committee has considered whether the provision of the non-audit services described above is compatible with maintaining the independence of Ernst & YoungGrant Thornton LLP and determined that such services are compatible with maintaining such independence.
The audit committee has adopted a policy whichthat requires pre-approval by the audit committee of all services to be provided by the Company'sCompany’s independent auditor.registered public accounting firm. The audit committee has approved the provision of audit services by Ernst & YoungGrant Thornton LLP for fiscal year 20042007 in accordance with that policy.policy and the Company’s use of Grant Thornton LLP for tax and related matters during 2007 on an as-needed basis in the normal course of business provided total associated billings do not exceed $15,000. All other services to be provided by the Company'sCompany’s independent auditor must be specifically pre-approved by the audit committee or a designated member of the audit committee.
Representatives of Ernst & YoungGrant Thornton LLP are expected to be present at the annual meeting with the opportunity to make a statement if they desire to do so and are expected to be available to respond to appropriate questions. If shareholdersstockholders fail to ratify the selection of Grant Thornton LLP as the independent registered public accounting firm for 2007, the audit committee and the board of directors will reconsider whether to retain that firm. Even if the selection is ratified, the audit committee and the board may, in itstheir discretion, may direct the appointment of a different independent auditorsregistered public accounting firm at any time during the year.
THE COMPANY'SCOMPANY’S BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDS A VOTE "FOR"“FOR” THE RATIFICATION OF THE APPOINTMENT OF ERNST & YOUNGGRANT THORNTON LLP AS THE COMPANY'SCOMPANY’S INDEPENDENT AUDITORSREGISTERED PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2004. VOTE REQUIRED The ratification of the appointment of Ernst & Young LLP requires the affirmative vote of a majority of the shares of common stock represented at the annual meeting and entitled to vote thereon. 7 EXECUTIVE COMPENSATION SUMMARY COMPENSATION TABLE The following table sets forth the compensation paid by us during 2001, 2002 and 2003 to our chief executive officer and our next four most highly compensated other executive officers who received salary compensation of more than $100,000 during 2003 (the "Named Executive Officers"). SUMMARY COMPENSATION TABLE
LONG-TERM COMPENSATION --------------- ANNUAL COMPENSATION SECURITIES ----------------------------- UNDERLYING ALL OTHER NAME PRINCIPAL POSITION(S) YEAR SALARY($) BONUS($) OPTIONS/SARS(#) COMPENSATION($) - ---- --------------------- ---- --------- ---------- --------------- --------------- Dr. Lance Fors......... Chief Executive 2003 $430,523 $ 200,000 220,000 $52,563(2) Officer, 2002 $398,239 $ 150,000 291,000 $ 2,826(2) Chairman, Director 2001 $384,790 $ 0 141,480 0 John J. Puisis(1)...... President, Chief 2003 $349,798 $ 200,000 480,000 $11,048(2) Operating Officer, 2002 $253,380 $ 150,000 145,000 $20,705(2) Director 2001 $ 65,587 $2,111,864 275,000 $ 4,924(2) Maneesh Arora(3)....... Senior Vice President 2003 $206,739 $ 110,000 350,000 $13,409(2) Ivan Trifunovich(4).... Senior Vice 2003 $263,693 $ 85,750 0 0 President & 2002 $260,713 $ 0 100,000 0 General Manager, 2001 $ 0 $ 0 210,000 0 Genomics Business Unit John Comerford......... Vice President, 2003 $223,198 $ 90,000 75,000 0 General Counsel & 2002 $209,879 $ 15,000 140,000 0 Secretary 2001 $200,461 $ 0 81,000 0
- --------------- (1) Mr. Puisis joined us in September 2001. (2) Consists of relocation expenses paid by us. (3) Mr. Arora joined us in January 2003 (4) Mr. Trifunovich joined us in December 2001. OPTION GRANTS IN 2003 The following table sets forth information relating to stock options granted during 2003 to the Named Executive Officers. In accordance with the rules of the Securities and Exchange Commission, also shown below is the potential realizable value over the term of the option (the period from the grant date to the expiration date) based on assumed rates of stock appreciation of 5% and 10%, compounded annually. These amounts are mandated by the Securities and Exchange Commission and do not represent our estimate of 8 future stock price. Actual gains, if any, on stock option exercises will depend on the future performance of our common stock.
INDIVIDUAL GRANTS ----------------------------------------------------- POTENTIAL REALIZABLE PERCENT OF VALUE AT ASSUMED NUMBER OF TOTAL ANNUAL RATES OF STOCK SECURITIES OPTIONS PRICE APPRECIATION FOR UNDERLYING GRANTED TO EXERCISE OPTION TERM OPTIONS EMPLOYEES IN PRICE PER EXPIRATION ----------------------- NAME GRANTED(#)(1) 2003(2) SHARE($) DATE 5%($) 10%($) - ---- ------------- ------------ --------- ---------- --------- ----------- Dr. Lance Fors.......... 220,000 7.8% 4.16 05/13/2013 575,564 1,458,593 John J. Puisis.......... 280,000 9.9% 2.69 01/01/2013 473,683 1,200,407 200,000 7.1% 4.00 07/17/2013 503,116 1,274,994 Maneesh Arora........... 175,000 6.2% 2.64 01/03/2013 290,549 736,309 25,000 0.9% 3.07 03/24/2013 48,268 122,320 25,000 0.9% 3.65 04/17/2013 57,387 145,429 125,000 4.4% 4.00 07/17/2013 314,447 796,871 Ivan Trifunovich........ 0 -- -- -- -- -- John Comerford.......... 75,000 2.7% 4.00 07/17/2013 188,668 478,123
- --------------- (1) For each of the Named Executive Officers, 25% of the options vest on each of the first four anniversaries of the grant date. (2) We granted options to purchase a total of 2,818,300 shares of common stock during 2003. AGGREGATE OPTION EXERCISES IN 2003 AND FISCAL YEAR-END OPTION VALUES The following table sets forth information for the Named Executive Officers relating to option exercises in 2003 and the number and value of securities underlying exercisable and unexercisable options held at December 31, 2003:
NUMBER OF SECURITIES UNDERLYING UNEXERCISED VALUE OF UNEXERCISED OPTIONS AT IN-THE-MONEY OPTIONS AT SHARES DECEMBER 31, 2003 DECEMBER 31, 2003($)(1) ACQUIRED ON VALUE --------------------------- --------------------------- NAME EXERCISE(#) REALIZED($) EXERCISABLE UNEXERCISABLE EXERCISABLE UNEXERCISABLE - ---- ----------- ----------- ----------- ------------- ----------- ------------- Dr. Lance Fors......... 0 0 537,959 449,641 506,631 613,965 John Puisis............ 0 0 173,750 726,250 87,725 893,975 Maneesh Arora.......... 0 0 0 350,000 0 462,500 Ivan Trifunovich....... 0 0 130,000 180,000 60,500 181,500 John Comerford......... 0 0 113,300 222,300 84,700 295,350
- --------------- (1) Value of unexercised in-the-money options are based on a value of $4.55 per share, the fair market value of our common stock on December 31, 2003. Amounts reflected are based on the value of $4.55 per share, minus the per share exercise price, multiplied by the number of shares underlying the option. EMPLOYMENT AGREEMENTS WITH EXECUTIVE OFFICERS In October of 2003 we entered into a three-year employment agreement with Dr. Fors that provides for an initial base salary of $400,000. The agreement also provides that Dr. Fors' employment may be terminated at any time by us or by Dr. Fors. If Dr. Fors' employment is terminated by us other than for "cause" (as defined in the agreement) or Dr. Fors voluntarily terminates his employment for "good reason" (as defined in the agreement), Dr. Fors would receive severance payments totaling 18 months of his then current base salary (6 months of which would be paid in an up front lump sum), any accrued and unpaid bonuses as of the date of termination and we would purchase an outplacement consulting package for Dr. Fors for up to a maximum of $15,000. If we do not elect to renew Dr. Fors employment at the end of his employment term, Dr. Fors would 9 receive an amount of severance pay equal to six months of his then current base salary, payable over 12 months and any accrued and unpaid bonuses. We have entered into an employment agreement with Mr. Puisis that provides for an initial base salary of $225,000 and a target annual bonus of no less than 22.5% of base salary. The agreement provided for an initial option grant to Mr. Puisis and for the one-time sign-on bonus to Mr. Puisis (the "Sign-on Bonus") listed under "Summary Compensation Table" to partially compensate Mr. Puisis for certain moneys lost upon Mr. Puisis beginning employment with us. Mr. Puisis' employment may be terminated by either us or Mr. Puisis at any time, except that if we terminate Mr. Puisis other than for "cause" or Mr. Puisis voluntarily terminates his employment for "good reason", Mr. Puisis would receive a lump sum severance payment equal to one year's base salary and a pro-rated portion of his target bonus and continued coverage for one year under our health and other welfare benefit plans. The employment agreement with Mr. Puisis defines "good reason" to include a resignation by Mr. Puisis following a "change of control" (as defined in the employment agreement), but not earlier than six months after the change in control. EQUITY COMPENSATION PLAN INFORMATION The following table summarizes the number of outstanding options granted to employees and directors, as well as the number of securities remaining available for future issuance, under our compensation plans as of December 31, 2003.
NUMBER OF SECURITIES REMAINING AVAILABLE FOR FUTURE ISSUANCE NUMBER OF SECURITIES WEIGHTED AVERAGE UNDER EQUITY TO BE ISSUED UPON EXERCISE PRICE COMPENSATION PLANS EXERCISE OF OUT- OF OUTSTANDING (EXCLUDING SECURITIES STANDING OPTIONS, OPTION WARRANTS REFLECTED IN THE PLAN CATEGORY WARRANTS AND RIGHTS AND RIGHTS FIRST COLUMN) - ------------- -------------------- ---------------- --------------------- Equity compensation plans approved by security holders......................... 7,256,505 $4.37 1,478,692 Equity compensation plans not approved by security holders......................... 0 0 0 --------- ----- --------- Total...................................... 7,256,505 $4.37 1,478,692 ========= ===== =========
BOARD 2007.
COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION The following report is provided to shareholders by the compensation committee of the board of directors:
The compensation committee of the board of directors has reviewed and discussed the below section titled“Executive Compensation — Compensation Discussion and Analysis” with management, and, based on such review and discussions, recommended to the board of directors that the section be included in this Proxy Statement and the Annual Report onForm 10-K for the year ended December 31, 2006.
Respectfully submitted,
The compensation committee of the board of directors.
Gordon Brunner
Lawrence Murphy
David Thompson
EXECUTIVE COMPENSATION
Compensation Discussion & Analysis
The following is a discussion and analysis of the material elements of our compensation program as it relates to our Chief Executive Officer, Chief Financial Officer and the other executive officers named in the Summary Compensation Table. See“Summary Compensation Table”on page 14 below. This discussion is intended to put into perspective the tables and other narrative disclosures that follow it.
Objectives of Executive Compensation Program
The primary objectives of our executive compensation program are:
• to provide competitive levels of total compensation that will enable us to attract and retain the best possible executive talent;
• to motivate executives to achieve optimum performance for the Company;
• to reward performance based on the attainment of our annual and long term strategic objectives;


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• to align the financial interest of executives and stockholders through equity-based plans; and
• to provide a total compensation program that recognizes individual contributions as well as overall business results.
Elements of Executive Compensation
Our compensation program consists of the following elements: base salaries, annual incentive awards and long term compensation including long term incentive plan awards and option awards. We also provide our executive officers certain perquisites and personal benefits. We have entered into employment agreements with our executive officers under which is composedthey are entitled to certain compensation and benefits. Our executive officers are also entitled to receive severance payments and other compensation upon the occurrence of three independent, non-employeecertain events related to a termination of employment or change of control.
The compensation committee of the board of directors (the “Committee”) is responsible for setting the administrationcompensation of all executive officers. In setting compensation levels, the Committee considers all elements of the Company'sexecutive compensation programs. These programs include base salaryprogram in total rather than each element in isolation. The Committee is guided by its own judgment and those sources of information (including compensation surveys) that the Committee considers relevant. From time to time, the Committee reviews summaries, sometimes referred to as “tally sheets,” reflecting each executive officer’s compensation history with respect to each element of compensation for service as an executive officersofficer, as well as projected payouts that would come due in connection with a change of control. The committee has used compensation consultants in past years to assist in developing compensation policies and both annual andpractices. During 2006, the Committee utilized two compensation consultants for various compensation related matters. For example, reviewing the Company’s long-term incentive compensation programs. The Company'sIn the future, the Committee may engage or seek the advice of compensation programs are designed to provide a competitive level of total compensation and include incentive and equity ownership opportunities linked to the Company's performance and shareholder return. Compensation Philosophy. The Company's overall executive compensation philosophy is based on a series of guiding principles derived from the Company's values, business strategy and management requirements. These principles are summarized as follows: - provide competitive levels of total compensation which will enable the Company to attract and retain the best possible executive talent; - motivate executives to achieve optimum performance for the Company; - align the financial interest of executives and shareholders through equity-based plans; and 10 - provide a total compensation program that recognizes individual contributions as well as overall business results. Compensation Program. The compensation committee is responsible for reviewing and recommending to the board the compensation and benefits of all officers of the Company and establishes and reviews general policies relating to compensation and benefits of employees of the Company. The compensation committee is also responsible for the administration of the Company's 2000 Stock Plan. There are two major components to the Company's executive compensation: base salary and potential cash bonus, as well as potential long-term compensation in the form of stock options and a long-term incentive plan. The compensation committee considers the total current and potential long-term compensation of each executive officer in establishing each element of compensation. 1. Base Salary. In setting compensation levels for executive officers, the compensation committee reviews competitive information to compensation levels for comparable positions at biotechnology and high technology companies.consultants. In addition, the compensation committee may form, and delegate authority to, subcommittees when it deems appropriate.
As a general principle, the Committee believes that compensation of the executive officers cannot always be based upon fixed formulas and that the prudent use of discretion in determining compensation will generally be in the best interests of Third Wave and its stockholders. Accordingly, from time to time hirein the exercise of its discretion, the Committee may approve changes in compensation that it considers to be appropriate to award performance or otherwise to provide incentives toward achieving the objectives of our executive compensation program.
Base Salary
Base salaries are paid to provide executives officers with a base level of monthly compensation and benefit consultants to assist in developingachieve our objectives of attracting and reviewing overall salary strategies. Individualretaining executive officertalent and rewarding performance. Our decisions regarding base compensation may varysalaries are based principally on time in position,our evaluation of the market demand for executives with similar capability and experience, assessment of individual performance salary relativein relation to internal and external fairness andour strategic objectives, our corporate performance, the critical nature of the position relative to the success of the Company. 2. Company, time in position and salary relative to internal and external fairness. We also seek to strike an appropriate balance between fixed elements of compensation, such as base salaries, and variable performance-based elements.
In setting base salary levels for executive officers, the Committee considers compensation levels for comparable positions at biotechnology companies as documented in the Radford Biotechnology Survey. We generally set base salary levels for executive officers at approximately the 50th percentile for the position as reflected in the Radford Survey.
Annual Incentive Awards. The Company does establish both corporateAwards
We provide our executive officers an annual incentive compensation plan to achieve our objectives of rewarding performance and motivating the executives to attain our strategic objectives. Target incentive awards are based principally on each executive’s level of responsibility in relation to our annual and long term objectives, recommendations of the chief executive officer, and stated targets under employment agreements. We also seek to strike an appropriate balance between fixed elements of compensation, such as base salaries, and variable performance-based elements. We set target incentive awards at levels that are designed to link a substantial


10


portion of each individual’s total annual compensation to attaining the performance objectives discussed below in order to provide appropriate incentives to attaining those objectives. In setting target incentive awards levels for executive officers, the Committee considers target incentive award levels for comparable positions at biotechnology companies as documented in the Radford Biotechnology Survey. We generally set target incentive awards levels for executive officers at or below the 75th percentile for the position as reflected in the Radford Survey.
Mr. Conroy’s employment agreement provides for a target annual incentive award opportunity equal to 50% of Mr. Conroy’s base salary, with the exact amount to be determined by the Committee. Mr. Arora’s employment agreement provides for a target bonus opportunity equal to 40% of Mr. Arora’s base salary, with the exact amount to be determined by the Committee. 2006 target annual incentive awards approved by the Committee for the named executive officers were as follows: Mr. Conroy 50%, Mr. Arora 40%, Mr. Trifunovich 35%, Mr. Garces 35% and Mr. Bellano 40%.
Based on the Company’s performance against established performance measures and individual goals andperformance against individual performance measures, consistent with factors necessaryeach of our executives is eligible to achieve strategic business objectives. Annualreceive from 0% to 200% of his or her target annual incentive awards paid to Company employees, including the executive officers,award. Performance measures and objectives are determined based on a combinationour business plan for the year in question. Such business plan is developed by management and approved by the board of directors. For the 2006 Incentive Plan, the Company performance objectives measured were net cash from operations (excluding changes in working capital) and total revenue. We adopted these performance measures because we believe they are key indicators of our financial and operational success and are key drivers of long-term stockholder value. Based on the achievement of the predetermined corporateCompany and individual performance goals, each of our executives received 150% of his or her 2006 target incentive award.
The Committee reserves discretion to adjust the way performance is measured against the targets to ensure payouts are not artificially inflated or deflated due to unexpected items. For example, in determining payouts under the 2006 plan, the Committee increased targets for net cash from operations so that payouts were not favorably impacted by our spending less on research and measures. The annualdevelopment in 2006 than was initially budgeted. In addition, the Committee retains discretion to determine not to pay any incentive plan awards are designed to drive individual andour executive officers notwithstanding achievement of Company performance goals.
In connection with its determination of the payouts to enhance shareholder value. 3. Long-Term Incentives. be made under the 2006 Incentive Plan, in January 2007 the Committee approved a program under which participants were given the option to take all or any portion of their 2006 incentive plan payout in the form of shares of the Company’s common stock. Under this program, to the extent a participant chose to accept a portion of his or her award in shares of common stock, then that portion of the award was increased by 15% and paid in shares of common stock based on the closing price of our common stock on the third trading day following public disclosure of our fourth quarter and full-year 2006 results of operations.
Long Term Equity Compensation
The Company'sCompany’s 2000 Stock Plan provides for the issuance of stock options to officers and employees of the Company to purchase shares of the Company'sCompany’s common stock. Additionally, under the 2000 Stock Plan we issue restricted stock at an exercise price equalunit awards that entitle non-executive employees to receive shares of stock as the fair market value of suchawards vest. We grant stock on the date of grant. Stock options are grantedand restricted stock units both to the Company's executive officersreward short-term performance with equity-based compensation and other employees both as a reward for past individual and corporate performance and as an incentive for futureto motivatelong-term performance. The compensation committeeCommittee believes that stock-based performance compensation arrangements are essential in aligning the interests of management and with the shareholdersstockholders in enhancing the value of the Company'sCompany’s equity.
We generally grant three different types of option awards to executive officers:
• new hire grants awarded as an inducement to join the Company;
• special awards granted fromtime-to-time in connection with promotions, to reward outstanding performance or as a retention tool; and
• annual awards granted in the early part of the year in connection with the annual performance review.
The Committee approves all option awards made to executive officers. See“Grants of Plan-Based Awards” below. Awards granted to an executive are based upon a number of factors, including the executive’s position and


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responsibilities, salary and individual performance as well as overall Company performance. In making awards we also take into account the dilutive affect of such awards, previous stock-based awards made to the executive, benchmarking information and the relationship of such awards to awards under our Long Term Incentive Plans which are also intended to provide long term incentives to our senior executives.
In connection with the annual performance review, Maneesh Arora, Ivan Trifunovich, John Bellano and Jorge Garces received 30,000, 30,000, 20,000 and 20,000 stock options, respectively. Additionally, in connection with a promotion, John Bellano received an additional 80,000 options in 2006. Because he received a grant of 250,000 options in December 2005 in connection with his promotion to chief executive officer, Kevin Conroy did not receive an option award in 2006. For additional information, see“Grants of Plan-Based Awards Table” on page 15 below.
In 2006, we began awarding restricted stock units to non-executive employees instead of stock options primarily because we concluded that restricted stock units would be less dilutive to stockholders and also because restricted stock units provide more certain value to employees than stock options. Because they were not executive officers at the time we initiated our restricted stock unit award program, each of John Bellano and Jorge Garces received the restricted stock unit awards detailed in the“Grants of Plan-Based Awards Table” on page 15 below. In January 2004,2007, the Company implemented a long-term incentive plan designedCommittee chose to encourage results oriented actions onsubstitute annual restricted stock unit awards for the part ofannual option program for our executive officers and other key employees offor the Company. The plan issame reasons.
Long Term Incentive Plans
We have long term incentive plans intended to align closely the financial rewards for executive officers and key employees with the interests of shareholdersstockholders and the achievement of specific performance objectives of the Company. This program isThe plans are administered by the Compensation Committee, which establishes the termterms of the plan,plans, performance goals, target awards, performance measurement criteria and calculation of awards. The long-term incentive plan isplans are also designed to reduce reliance on stock option grants as the sole source of long-termlong term incentive compensation. 4. Benefits. The
Our first long term incentive plan was established in January 2004. This plan covered the period from2004-2006. Plan awards were payable in cash or Company provides benefits to the Named Executive Officers that are generally available to all employees of the Company. The amount of executive level benefitscommon stock only if and perquisites, as determined in accordance with the rules of the Securities and Exchange Commission relating to executive compensation, did not exceed 10% of total salary and bonus for the calendar year 2003 for any executive officer. Section 162(m) of the Internal Revenue Code Limitations on Executive Compensation. Section 162(m) of the United States Internal Revenue Code may limit the Company's ability to deduct for United States federal income tax purposes compensation in excess of $1,000,000 paid to the Company's chief executive officer and its four other highest paid executive officers in any one fiscal year. No executive officer of the Company received any such compensation in excess of this limit during fiscal 2003. 11 The total compensation of Dr. Fors, the Company's Chief Executive Officer, is consistent with the Company's overall executive compensation philosophy as described above, and the compensation of Dr. Fors was based on the factors described above. It is the opinion of the compensation committee that the aforementioned compensation policies and structures provide the necessary discipline to properly align the Company's corporate economic performance and the interest of the Company's shareholders with progressive, balanced and competitive executive total compensation practices in an equitable manner. The foregoing report shall not be "soliciting material" or to be "filed" with the Securities and Exchange Commission, nor shall such information be incorporated by reference into any future filing under this Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, except to the extent the Company specifically incorporatesattained clinical revenue, stock price and total shareholder return versus peer group performance goals set by the Committee for the performance period. Based on the Company’s performance against the performance goals, no payouts were made on plan awards.
Second, third and fourth long term incentive plans were established in February 2005, March 2006 and March 2007, respectively. The plans cover the periods from2005-2007,2006-2008 and2007-2009, respectively. Plan awards will become payable in cash or Company common stock if and to the extent the Company attains the revenue, stock price and total shareholder return versus peer group performance goals set by the Committee for the relevant performance period as reflected in the plans. We adopted these performance measures because we believe they are key indicators of our financial and operational success and are key drivers of long-term stockholder value.
When the Committee establishes a long term incentive plan it also determines the target award under the plan for each executive officer, which generally equals three or four times the highest target annual incentive award for the executive during the performance period. The potential payouts on plan awards range from 0% to 200% of the target award based on the Company’s performance against the performance goals. Subject to continued employment during such period, earned awards are payable in cash or in shares of Company common stock over a two-year period following completion of the performance period. For further information, see“Grant of Plan-Based Awards Table” on page 15 below. Each of our long term incentive plans provide for deemed satisfaction of performance goals and accelerated vesting in the event of a change of control of the Company during a performance period as described under“Potential Payments Upon Termination or Change of Control” on page 20 below.
Perquisites and Personal Benefits
We provide our employees, including our executive officers, with a benefit program that we believe is reasonable, competitive and consistent with the objectives of the compensation program of attracting and retaining talented executives with the skills and attributes that we need.


12


Our executive officers are eligible to participate in our group insurance program, which includes group health, dental, life and long term disability insurance. Our executives are required to pay most of the premiums associated with coverage under these plans. We make cash payments to our executives under a flexible benefits plan that is intended to provide them with funds they may use to pay these premiums. Other benefits include a 401(k) plan, relocation expense reimbursement and a related tax-reimbursement program under which taxes associated with relocation benefits are reimbursed by referencethe Company. See“Summary Compensation Table” on page 14 below.
Employment Agreements
We have entered into such filing. Respectfully submitted, employment agreements with our executive officers under which they are entitled to certain compensation and benefits. These agreements are intended to provide employment security by specifying minimum base salary, target annual and long term incentive plan award levels and severance benefits. Additionally, under these agreements our executive officers agree to certain non-competition and non-solicitation covenants. See“Employment Agreements with Named Executive Officers” on page 17 below.
Payments and Benefits Upon Change of Control
We have established various arrangements with our executive officers under which payments and benefits would come due in connection with a change of control of the Company. We established these arrangements for the following reasons:
• We believe that it is in the best interests of the Company and its stockholders to assure that the Company will have the continued dedication of our executive officers notwithstanding the possibility, threat or occurrence of a change of control;
• We believe it is imperative to diminish the inevitable distraction to such executive officers by virtue of the personal uncertainties and risks created by a pending or threatened change of control; and
• To provide the executive officers compensation and benefits arrangements upon a change of control which ensure that the compensation and benefits expectations of the executive officers will be satisfied and which are competitive with those of other similarly-situated companies.
These arrangements include:
• Additional severance payments in connection with certain kinds of termination;
• Accelerated vesting of stock options; and
• Deemed satisfaction of performance goals and accelerated vesting under our long term incentive plans.
See“Potential Payments Upon Termination or Change of Control” on page 20 below.
In establishing these arrangements we have considered the potential costs that could be incurred by the Company in connection with a change of control. On a regular basis, the Committee reviews the total amounts that would be payable under our long term incentive plans in connection with a change of control.


13


Summary of Compensation and Grants of Plan-Based Awards
The following table sets forth information concerning the compensation committeeearned during 2006 by our Chief Executive Officer, our Chief Financial Officer and our three most highly compensated executive officers other than the Chief Executive Officer and the Chief Financial Officer during the fiscal year ended December 31, 2006 (collectively, the “named executive officers”).
2006 Summary Compensation Table
                         
           Non-Equity
       
           Incentive
  All Other
    
     Stock
  Option
  Plan Comp-
  Comp-
    
  Salary
  Awards
  Awards
  ensation
  ensation
  Total
 
Name and Principal Position
 ($)  ($)(1)  ($)(2)  (3)  ($)(4)  ($) 
 
Kevin Conroy  375,000      311,911   282,769   70,363   1,040,043 
President, CEO and Director                        
Maneesh Arora  268,125      317,621   159,000   40,888   785,634 
Chief Financial Officer                        
Ivan Trifunovich  265,000      105,509   149,559   17,470   537,538 
Senior Vice President                        
Jorge Garces  181,250   49   57,702   97,999   15,518   352,518 
Vice President, Research & Development                        
John Bellano  170,933   2,897   39,041   105,000   25,496   343,367 
Vice President, Sales                        
(1)The amounts shown in this column indicate the dollar amount of compensation cost recognized by us for financial statement reporting purposes in 2006 pursuant to FAS 123R for restricted stock units in 2006. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting conditions. For additional information regarding the assumptions made in calculating these amounts, see Note 2 to the consolidated financial statements included in our Annual Report onForm 10-K for the year ended December 31, 2006. These amounts reflect the Company’s accounting expense for these awards, and do not correspond to the actual value that will be recognized by the named executive officers.
(2)The amounts shown in this column indicate the dollar amount of compensation cost recognized by us for financial statement reporting purposes in 2006 pursuant to FAS 123R for stock option awards granted in 2006 and in prior years. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting conditions. For additional information regarding the assumptions made in calculating these amounts for options granted from2004-2006, see Note 2 to the consolidated financial statements included in our Annual Report onForm 10-K for the year ended December 31, 2006. For additional information regarding the assumptions made in calculating these amounts for options granted prior to 2004, see Note 5 to the consolidated financial statements included in our Annual Report onForm 10-K for the year ended December 31, 2003. These amounts reflect the Company’s accounting expense for these awards, and do not correspond to the actual value that will be recognized by the named executive officers.
(3)Represents payout under 2006 Incentive Plan. As described under“2006 Incentive Plan” below, participants in the 2006 Incentive Plan were given the option to take all or any portion of their plan award in shares of the Company’s common stock. Common stock taken in partial payment 2006 Incentive Plan awards was as follows: Mr. Conroy — $11,644; Mr. Trifunovich — $79,997; and Mr. Garces — $6,702.
(4)The amounts set forth in this column consisted of (i) relocation expense reimbursements, (ii) tax reimbursements, (iii) matching contributions to our 401(k) Plan, (iv) car allowance, and (v) contributions to our flexible benefits plan as follows:


14


                         
     Tax
  Matching
     Flexible
    
     Reimbursements
  Contribution to
  Car
  Benefits
    
  Relocation ($)  ($)  401(k) Plan ($)  Allowance ($)  Contribution ($)  Total ($) 
 
Kevin Conroy  42,854   8,640   6,600      12,269   70,363 
Maneesh Arora  22,394   785   6,600      11,108   40,888 
Ivan Trifunovich        6,600      10,870   17,470 
Jorge Garces        5,793      9,725   15,518 
John Bellano        6,297   9,600   9,598   25,495 
The following table sets forth information concerning grants of plan-based awards made to the named executive officers during 2006.
2006 Grants Of Plan-Based Awards
                                         
                    All Other
          
                    Option
          
                 All Other
  Awards:
        Grant
 
                 Stock
  Number of
  Exercise
     Date Fair
 
           Estimated Future
  Awards:
  Securities
  or Base
  Market
  Value of
 
           Payouts Under Non-
  Number of
  Under-
  Price of
  Price on
  Stock and
 
           Equity Incentive Plan Awards  Shares of
  lying
  Option
  Date of
  Option
 
     Grant
  Approval
  Target
  Maximum
  Stock or
  Options
  Awards
  Grant
  Awards
 
Name
 Plan  Date(5)  Date(5)  ($)  ($)  Units(#)  (#)  ($/Sh)  ($/Sh)  ($)(6) 
 
Kevin Conroy  (1)          187,500   375,000                     
   (2)          850,000   1,700,000                     
Maneesh Arora  (1)          106,000   212,000                     
   (2)          440,000   880,000                     
   (3)  06/07/06   02/14/06               30,000   2.84   2.95   54,600 
Ivan Trifunovich  (1)          92,750   185,500                     
   (2)          288,750   577,500                     
   (3)  06/07/06   02/14/06               30,000   2.84   2.95   54,600 
Jorge Garces  (1)          64,750   129,500                     
   (2)          264,000   528,000                     
   (3)  06/07/06   05/18/06               20,000   2.84   2.95   36,400 
   (4)  06/07/06   05/18/06           112               334 
John Bellano  (3)  02/13/06   02/14/06               80,000   2.76   2.81   147,200 
   (1)          70,000   140,000                     
   (2)          234,000   468,000                     
   (3)  06/07/06   05/18/06               20,000   2.84   2.95   36,400 
   (4)  06/07/06   05/18/06           6,666               19,865 
(1)Represents 2006 Incentive Plan award. The 2006 Incentive Plan did not include a threshold performance level under which a minimum amount would be payable for a certain level of performance. For further information see“2006 Incentive Plan” below.
(2)Represents Long Term Incentive Plan No. 3 award. The Long Term Incentive Plan No. 3 does not include a threshold performance level under which a minimum amount would be payable for a certain level of performance. Target and maximum awards are based on a multiple of the highest target annual incentive award for the executive during the performance period. The target and maximum amounts included in this row take into account target awards for 2006 and 2007 but these amounts could increase based on 2008 target annual incentive awards. For further information see“Long Term Incentive Plan No. 3” below.
(3)Represents a Stock Option Award. For further information see“Stock Option Awards” below.
(4)Represents a Restricted Stock Unit Award. For further information see“Restricted Stock Unit Awards” below.
(5)Annual option awards for the named executive officers were approved on February 14, 2006 and May 18, 2006 by the compensation committee and the chief executive officer, respectively. However, the awards were not issued until June 7, 2006 following the board of directors’ approval of the amended and restated 2000 Stock

15


Plan and a new form of stock option agreement. Based on the Company’s voluntary review of its stock option grant practices (as described in the Company’sForm 10-Q for the quarter ended September 30, 2006), due to administrative error the 80,000 share stock option grant to John Bellano was incorrectly dated February 13, 2006 instead of February 14, 2006. In November 2006 we adopted an option granting policy we believe will ensure that measurement-date errors do not occur in the future. Restricted stock unit awards were approved by the chief executive officer on May 18, 2006. However the awards were not issued until June 7, 2006 following the board of directors’ approval of a form of restricted stock purchase agreement.
(6)The amounts shown in this column indicate the full grant date fair value of stock and option awards computed in accordance with FAS 123R. Generally, the full grant date fair value is the amount that we would expense in our financial statements over the award’s vesting schedule. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeitures related to service-based vesting conditions. For additional information regarding the assumptions made in calculating these amounts, see Note 2 to the consolidated financial statements included in our Annual Report onForm 10-K for the year ended December 31, 2006.
2006 Incentive Plan
In 2006, the named executive officers participated in the 2006 Incentive Plan. The 2006 target annual incentive awards for the named executive officers were as follows: Mr. Conroy, 50% of base salary ($187,500); Mr. Arora, 40% of base salary ($106,000); Mr. Trifunovich, 35% of base salary ($92,750); Mr. Garces, 35% of base salary ($64,750); and Mr. Bellano, 40% of base salary ($70,000).
Based on the Company’s performance against established performance measures and individual performance against individual performance measures, each of our executives was eligible to receive from 0% to 200% of his or her target annual incentive award. Performance measures and objectives for our incentive plans are determined based on our business plan for the year in question. Such business plan is developed by management and approved by the board of directors. For the 2006 Incentive Plan, the Company performance objectives measured were net cash from operations (excluding changes in working capital) and total revenue. Based on the achievement of Company and individual performance goals, each of our executives received 150% of his or her 2006 target incentive award.
In connection with its determination of the payouts to be made under the 2006 Incentive Plan, in January 2007 the Committee approved a program under which participants were given the option to take all or any portion of their 2006 incentive plan payout in the form of shares of the Company’s common stock rather than cash. Under this program, to the extent a participant chose to accept a portion of his or her award in shares of common stock that portion of the award was increased by 15% and paid in shares of common stock based on the closing price of our common stock on the third trading day following public disclosure of our fourth quarter and full-year 2006 results of operations.
Long Term Incentive Plan No. 3
During 2006, the named executive officers were granted awards under our Long Term Incentive Plan No. 3 covering the period from2006-2008. Plan awards will become payable in cash or Company common stock if and to the extent the Company attains the clinical revenue, stock price and total shareholder return versus peer group performance goals set by the Committee for the relevant performance period as reflected in the plan. For a detailed description of the plan’s performance goals and related payout amounts see Exhibit A attached to the copy of the plan filed as exhibit 10.30 with ourForm 10-K for the year ended December 31, 2005.
For each of Mr. Conroy and Mr. Arora, the target award under the plan equals four times the highest target annual incentive award for the executive during the performance period of2006-2008. For each other executive, the target award under the plan equals three times the highest target annual incentive award for the executive during such performance period.
Subject to continued employment during the performance period, earned awards are payable in cash or Company common stock over a two-year vesting period following completion of the performance period. To the extent a participant chooses to accept a portion of his or her award in shares of common stock, that portion of the award would be increased by 10% and paid in shares of common stock based on the price of our common stock five business days before the date of distribution. Except as described below, an earned award vests twenty-five percent


16


on the day it is earned (the last day of the performance period), fifty percent on the first anniversary of such date and twenty-five percent on the second anniversary of such date, provided the participant continues to be employed by the Company through the applicable vesting date. If a participant retires at or after his or her normal retirement age, becomes disabled, or dies during the performance period, the participant would be entitled to a prorated award based upon the Company’s performance during the performance period which award would fully vest at the end of the performance period. If a participant retires at or after his or her normal retirement age, becomes disabled, or dies after earning an award, the participant’s award fully vests at the time such event occurs.
The plan provides for deemed satisfaction of performance goals and accelerated vesting in the event of a change of control of the Company during the performance period as described under“Potential Payments Upon Termination or Change of Control” on page 20 below.
Stock Option Awards
We grant options under our 2000 stock plan. For each of the named executive officers, 25% of the options vest on each of the first four anniversaries of the grant date; provided vesting may accelerate in connection with certain termination events or a change of control as described under“Potential Payments Upon Termination or Change of Control” on page 20 below. Under the terms of the 2000 stock plan, as in effect during 2006, the exercise price for option awards was generally set at the closing price for the Company’s common stock on the date prior to the date of grant. In January 2007, the plan was amended to change this provision so that the exercise price for option awards is now generally set at the closing price for the Company’s common stock on the date of grant.
Restricted Stock Unit Awards
In February 2006, the Committee approved the addition of a restricted stock unit component to the Company’s equity compensation program. Under this program, the Company issues restricted stock units representing the right to purchase shares of Common Stock for $.001 per share as the award vests. For the named executive officers who received a restricted stock unit award, the awards vest over four years, with one-fourth vesting on each of the first, second, third and fourth anniversaries of the grant date; provided vesting may accelerate in connection with certain termination events or a change of control as described under“Potential Payments Upon Termination or Change of Control” on page 20 below.
Employment Agreements with Named Executive Officers
Kevin Conroy
Mr. Conroy and the Company entered into an amended employment agreement in December 2005 under which Mr. Conroy is entitled to a minimum base salary (currently $425,000) and a target annual incentive plan award opportunity equal to 50% of Mr. Conroy’s base salary, with the exact amount to be determined by the Committee. Under his agreement, Mr. Conroy participates in our long term incentive plans, participates in the benefits programs generally provided to our similarly situated employees, receives four weeks of paid vacation each calendar year, is entitled to reimbursement for up to $60,000 in relocation expenses (plus, to the extent such expenses are not tax deductible by Mr. Conroy, an associated taxgross-up) and reasonable and necessaryout-of-pocket business expenses and was granted 250,000 stock options. Under his agreement, Mr. Conroy would be entitled to certain payments and benefits in connection with certain termination events or a change of control as described under“Potential Payments Upon Termination or Change of Control” on page 20 below. The agreement also prohibits Mr. Conroy from engaging in certain activities involving competition with us for an18-month period following termination of his employment with the Company.
Maneesh Arora
In May 2005, the Company entered in to an employment agreement with Maneesh Arora under which Mr. Arora is entitled to a minimum base salary (currently $275,000) and a target annual incentive plan award opportunity equal to 40% of such base salary. Under his agreement, which was amended in March 2007, Mr. Arora participates in our long term incentive plans, participates in the benefits programs generally provided to our


17


similarly situated employees, receives four weeks of paid vacation each calendar year, is entitled to reimbursement for up to $75,000 in relocation expenses (plus, to the extent such expenses are not tax deductible by Mr. Arora, an associated taxgross-up) and reasonable and necessaryout-of-pocket business expenses. Under his agreement, Mr. Arora would be entitled to certain payments and benefits in connection with certain termination events or a change of control as described under“Potential Payments Upon Termination or Change of Control” on page 20 below. The agreement also prohibits Mr. Arora from engaging in certain activities involving competition with us for a12-month period following termination of his employment with the Company.
Ivan Trifunovich
In December 2001, the Company entered in to an offer letter with Ivan Trifunovich under which he was hired as Senior Vice President and is being paid a base salary of $275,000. Under the terms of the offer letter, Mr. Trifunovich would be entitled to certain payments and benefits in connection with certain termination events as described under“Potential Payments Upon Termination or Change of Control” on page 20 below.
Jorge Garces and John Bellano
In March 2007, the Company entered in to an employment agreement with each of Jorge Garces and John Bellano under which they are entitled to a minimum base salary (currently $220,000 and $195,000, respectively), and target annual incentive plan award opportunities equal to 40% of such base salaries. Under these agreements, Messrs. Garces and Bellano participate in our long term incentive plans, participate in the benefits programs generally provided to our similarly situated employees, receive four weeks of paid vacation each calendar year and are entitled to reimbursement for reasonably incurredout-of-pocket business expenses. Under these agreements, Messrs. Garces and Bellano would be entitled to certain payments and benefits in connection with certain termination events or a change of control as described under“Potential Payments Upon Termination or Change of Control” on page 20 below. The agreements also prohibit Messrs. Garces and Bellano from engaging in certain activities involving competition with us for either a six or12-month period following termination of employment with the Company.
2006 Outstanding Equity Awards At Fiscal Year End
The following table sets forth information concerning option award and stock awards held by the named executive officers as of December 31, 2006.
                         
  Option Awards  Stock Awards 
                 Market
 
                 Value of
 
  Number of
  Number of
           Shares or
 
  Securities
  Securities
        Number of
  Units of
 
  Underlying
  Underlying
  Option
     Shares or Units
  Stock That
 
  Unexercised
  Unexercised
  Exercise
  Option
  of Stock that
  Have Not
 
  Options (#)
  Options (#)
  Price
  Expiration
  Have Not Vested
  Vested
 
Name
 Exercisable  Unexercisable  ($)  Date  (#)  ($) 
 
Kevin Conroy  60,000   60,000(1) $4.53   07/12/14         
   50,000   50,000(2) $3.19   07/26/14         
   75,000     $6.88   10/28/14         
   16,250   48,750(3) $4.23   04/29/15         
   62,500   187,500(4) $2.82   12/29/15         
Maneesh Arora  112,500   37,500(5) $2.64   01/03/13         
   18,750   6,250(5) $3.15   01/03/13         
   18,750   6,250(6) $3.97   03/24/13         
   18,750   6,250(7) $3.65   04/17/13         
   93,750   31,250(8) $4.00   07/17/13         
   25,000   25,000(9) $4.55   02/25/14         
   9,167   9,167(10) $4.47   02/25/14         
   15,000   45,000(11) $4.23   04/29/15         
      30,000(12) $2.84   06/07/16         


18


                         
  Option Awards  Stock Awards 
                 Market
 
                 Value of
 
  Number of
  Number of
           Shares or
 
  Securities
  Securities
        Number of
  Units of
 
  Underlying
  Underlying
  Option
     Shares or Units
  Stock That
 
  Unexercised
  Unexercised
  Exercise
  Option
  of Stock that
  Have Not
 
  Options (#)
  Options (#)
  Price
  Expiration
  Have Not Vested
  Vested
 
Name
 Exercisable  Unexercisable  ($)  Date  (#)  ($) 
 
Ivan Trifunovich  210,000     $6.47   12/14/11         
   100,000     $2.13   06/13/12         
   10,000   10,000(13) $4.55   02/27/14         
   6,000   6,000(14) $4.47   03/26/14         
   18,750   56,250(15) $4.23   04/29/15         
      30,000(12) $2.84   06/07/16         
Jorge Garces  12,500   37,500(16) $4.95   10/03/15         
   6,250   18,750(17) $2.68   11/17/15         
      20,000(18) $2.84   06/07/16         
                   112 (19)  539 
John Bellano     80,000(20) $2.76   02/13/16         
      20,000(18) $2.84   06/07/16         
                   6,666 (21)  32,063 
(1)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 30,000 shares beginning on July 12, 2007.
(2)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 25,000 shares beginning on July 26, 2007.
(3)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 16,250 shares beginning on April 29, 2007.
(4)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 62,500 shares beginning on December 29, 2007.
(5)This item sets forth the unvested portion of an option grant, which will vest in full on January 3, 2007.
(6)This item sets forth the unvested portion of an option grant, which will vest in full on March 24, 2007.
(7)This item sets forth the unvested portion of an option grant, which will vest in full on April 17, 2007.
(8)This item sets forth the unvested portion of an option grant, which will vest in full on July 17, 2007.
(9)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 12,500 shares beginning on February 25, 2007.
(10)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 4,583 shares beginning on February 25, 2007.
(11)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 15,000 shares beginning on April 29, 2007.
(12)This item sets forth the unvested portion of an option grant, which will vest in four equal annual installments of 7,500 shares beginning on June 7, 2007.
(13)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 5,000 shares beginning on February 27, 2007.
(14)This item sets forth the unvested portion of an option grant, which will vest in two equal annual installments of 3,000 shares beginning on March 26, 2007.
(15)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 18,750 shares beginning on April 29, 2007.
(16)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 12,500 shares beginning on October 3, 2007.

19


(17)This item sets forth the unvested portion of an option grant, which will vest in three equal annual installments of 6,250 shares beginning on November 17, 2007.
(18)This item sets forth the unvested portion of an option grant, which will vest in four equal annual installments of 5,000 shares beginning June 7, 2007.
(19)This item sets forth the unvested portion of a restricted stock unit grant, which will vest in four equal annual installments of 28 shares beginning on June 7, 2007.
(20)This item sets forth the unvested portion of an option grant, which will vest in four equal annual installments of 20,000 shares beginning on June 7, 2007.
(21)This item sets forth the unvested portion of a restricted stock unit grant, which will vest in four equal annual installments of 1,667 shares beginning on June 7, 2007.
Potential Payments upon Termination or Change of Control
We have entered into employment agreements and maintain certain plans that will require us to provide compensation or other benefits to the named executive officers in connection with certain events related to a termination of employment or change of control.
Conroy Employment Agreement
Under his employment agreement, Mr. Conroy would, upon termination without “cause”, resignation for “good reason” or certain “change of control” events, receive certain severance benefits.
Under Mr. Conroy’s employment agreement, “cause” is defined as:
• any willful failure or refusal to perform his duties which continues after notice and an opportunity to cure;
• the commission of any fraud, embezzlement or other material act of dishonesty in connection with his employment;
• any gross negligence or willful misconduct with regard to the Company resulting in a material economic loss;
• a conviction of, or plea of guilty to, a felony or other crime involving moral turpitude;
• a misdemeanor conviction, the circumstances of which involve fraud, dishonesty or moral turpitude and which is substantially related to his employment;
• any willful and material violation of any statutory or common law duty of loyalty to the Company; or
• any material breach by Mr. Conroy of the employment agreement, including his obligations with respect to confidentiality and non-competition.
Under Mr. Conroy’s employment agreement, “good reason” is defined as:
• reduction of base salary in a manner that is not applied proportionately to other senior executive officers of the Company, or any such reduction that exceeds 30% of his then current base salary;
• a material reduction of his duties, authority or responsibilities or the assignment of duties inconsistent with the scope of authority, duties and responsibilities of his position;
• the occurrence of a material breach by the Company of any of its obligations under the agreement; or
• the Company materially violates or continues to materially violate any law or regulation contrary to Mr. Conroy’s and the Company’s outside counsel’s written advice and the Company fails to rectify such violation.


20


Under Mr. Conroy’s employment agreement, “change of control” is defined as:
• any person or group acting in concert, other than a trustee or other fiduciary holding securities under a Company employee benefit, becoming the beneficial owner, directly or indirectly, of Company securities representing more than 50% of the total voting power represented by the Company’s then voting securities;
• during any period of two consecutive years, individuals who at the beginning of such period constitute the board of directors of the Company and any new director whose election by the board of directors or nomination for election by the Company’s stockholders was approved by a vote of at least two-thirds of the directors then still in office, who either were directors at the beginning of the period or whose election or nomination for election was previously so approved, cease for any reason to constitute a majority of the board of directors;
• the Company’s stockholders approve a merger or consolidation of the Company with any other corporation, other than a merger or consolidation which would result in the Company’s voting securities outstanding immediately prior to such transaction continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity) at least 80% of the total voting power represented by the Company’s voting securities or such surviving entity outstanding immediately after such merger or consolidation; or
• the Company’s stockholders approve a plan of complete liquidation of the Company or an agreement for the sale or disposition by the Company of (in one transaction or a series of related transactions) all or substantially all of the Company’s assets.
Under Mr. Conroy’s employment agreement, upon termination without cause or resignation for good reason, Mr. Conroy would become entitled to receive:
• severance pay for a period of 18 months at his then current base salary; provided, that if termination occurs within twelve months before or after a change of control, severance would be payable for 24 months from the later of termination and the effective date of the change of control;
• any accrued but unpaid base salary and annual incentive bonus as of the termination date;
• the pro rata portion of target annual incentive bonus, provided that an annual incentive bonus is paid to other senior executives of the Company at the end of the applicable year;
• if termination occurs within one year following a change of control, the pro rata portion of the target annual incentive bonus, regardless of whether or not an annual incentive bonus is paid to other senior executives of the Company;
• if Mr. Conroy elects COBRA coverage for healthand/or dental insurance, the monthly premium payments for such coverage until the earlier of: (1) 12 months from the termination date; (2) Mr. Conroy obtains employment offering healthand/or dental coverage comparable to that offered by the Company; or (3) the date COBRA coverage would otherwise terminate;
• an outplacement consulting package up to a maximum of $10,000;
• a pro rata portion of any long term incentive plan awards that are earned based on the satisfaction of performance targets set forth in such plans and without the requirement of continued employment;
• accelerated vesting of 50% of then unvested stock and option awards; and
• a change in the exercise period for vested options such that vested options become exercisable until the earlier of (1) two years from termination of employment and (2) expiration of the original option term.
Under Mr. Conroy’s employment agreement, in connection with a change of control:
• the amount of severance to which Mr. Conroy would be entitled would be increased as described above;
• in the event Mr. Conroy’s employment is terminated by the Company without cause or by Mr. Conroy for good reason within 12 months before or after the change of control, any long term incentive plan awards


21


made to Mr. Conroy would become payable as described under“Long Term Incentive Plans” below notwithstanding such termination of employment as if Mr. Conroy were employed as of the effective date of the change of control;
• outstanding unvested stock and option awards held by Mr. Conroy would be accelerated as provided in the applicable award agreements provided that at a minimum at least 50% of such unvested stock and option awards would become immediately vested and exercisable;
• if Mr. Conroy’s employment was terminated (other than termination for cause or resignation without good reason) within 12 months before the change of control, any unvested options or stock awards forfeited in connection with such termination would become vested as if Mr. Conroy were employed as of the effective date of the change of control; and
• any payments due Mr. Conroy as a result of a change of control would begrossed-up so that the net amount retained by him, after deduction of any parachute payment excise taxes, would equal the amounts payable as described above.
Arora Employment Agreement
Under his employment agreement, Mr. Arora would, upon termination without “cause,” resignation for “good reason” or certain “change of control” events, receive certain severance benefits.
Under Mr. Arora’s employment agreement, “cause” has substantially the same meaning as it does in Mr. Conroy’s agreement (described above).
Under Mr. Arora’s employment agreement, “good reason” has substantially the same meaning as it does in Mr. Conroy’s agreement (described above) except that the definition contained in Mr. Arora’s agreement does not include the Company’s materially violating any law or regulation contrary to Mr. Arora’s and the Company’s outside counsel’s written advice and the Company failing to rectify such violation.
Under Mr. Arora’s employment agreement, upon termination without cause or resignation for good reason Mr. Arora would become entitled to receive:
• severance pay in a lump-sum equal to 12 months base salary;
• any accrued but unpaid base salary and annual incentive plan award as of the termination date;
• the pro rata portion of target annual incentive bonus, provided that an annual incentive bonus is paid to other senior executives of the Company at the end of the applicable year;
• if termination occurs within one year following a change of control, the pro rata portion of the target annual incentive bonus, regardless of whether or not an annual incentive bonus is paid to other senior executives of the Company;
• if Mr. Arora elects COBRA coverage for healthand/or dental insurance, the monthly premium payments for such coverage until the earlier of: (1) 12 months from the termination date; (2) Mr. Arora obtains employment offering healthand/or dental coverage comparable to that offered by the Company; or (3) the date COBRA coverage would otherwise terminate;
• an outplacement consulting package up to a maximum of $10,000;
• payment of any previously earned long term incentive plan awards, whether vested or unvested; and
• a change in the exercise period for vested options such that vested options become exercisable until the earlier of (1) two years from termination of employment and (2) expiration notwithstanding such termination of employment.


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Under Mr. Arora’s employment agreement, “change of control” is defined in the same manner as in Mr. Conroy’s employment agreement, described above. Under Mr. Arora’s employment agreement, in connection with a change of control:
• Mr. Arora would be entitled to receive the pro rata portion of the target annual incentive bonus, regardless of whether or not an annual incentive bonus is paid to other senior executives of the Company;
• in the event Mr. Arora’s employment is terminated by the Company without cause or by Mr. Arora for good reason within six months before or 12 months after the change of control, any long term incentive plan awards made to Mr. Arora would become payable as described below notwithstanding such termination of employment as if Mr. Arora were employed as of the effective date of the change of control;
• outstanding unvested stock and option awards held by Mr. Arora would be accelerated as provided in the applicable award agreements provided that at a minimum at least 50% of such unvested stock and option awards would become immediately vested and exercisable; and
• if Mr. Arora’s employment was terminated (other than termination for cause or resignation without good reason) within six months before the change of control, any unvested options or stock awards forfeited in connection with such termination would become vested as if Mr. Arora were employed as of the effective date of the change of control.
Trifunovich Offer Letter
Under his employment agreement, Mr Trifunovich is entitled to be paid one year of base salary as severance in the event (1) his employment is terminated by the Company or (2) the Company adversely changes the terms of his employment from those described in the letter, the Company does not cure such adverse change within 30 days after notice and thereafter Mr. Trifunovich chooses to terminate his employment.
Bellano and Garces Employment Agreements
Under their employment agreements, Messrs. Garces and Bellano would, upon termination without “cause,” resignation for “good reason” or certain “change of control” events, receive certain severance benefits.
Under Messrs. Garces’ and Bellano’s employment agreements, the terms “cause” and “good reason” have substantially the same meanings as they do in Mr. Conroy’s agreement (described above).
Under their employment agreements, upon termination without cause or resignation for good reason Messrs. Garces and Bellano would become entitled to receive:
• severance pay in a lump-sum equal to six months base salary; provided that if termination occurs within six months before or 12 months after a change of control, severance would be payable for 12 months from the later of termination and the effective date of the change of control; and
• any accrued but unpaid base salary and annual incentive plan award as of the termination date.
Under Messrs. Garces’ and Bellano’s employment agreements, “change of control” is defined in the same manner as in Mr. Conroy’s employment agreement, described above.
Under these employment agreements, in connection with a change of control:
• the amount of severance to which Messrs. Garces and Bellano would be entitled would be increased as described above;
• if COBRA coverage for health and/or dental insurance is elected, the monthly premium payments for such coverage until the earlier of: (1) 6 months from the termination date; (2) obtains employment offering health and/or dental coverage comparable to that offered by the Company; or (3) the date COBRA coverage would otherwise terminate;
• in the event the executive is terminated by the Company without cause or by him for good reason within six months before a change of control, any long term incentive plan awards made to him would become payable


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as described under“Long Term Incentive Plans” below notwithstanding such termination of employment as if he was employed as of the effective date of the change of control;
• outstanding unvested stock and option awards held by Messrs. Garces and Bellano would be accelerated as provided in the applicable award agreements provided that at a minimum at least 50% of such unvested stock and option awards would become immediately vested and exercisable; and
• if the executive’s employment was terminated (other than termination for cause or resignation without good reason) within six months before the change of control, any unvested options or stock awards forfeited in connection with such termination would become vested as if the executive were employed as of the effective date of the change of control.
Conditions to Receipt of Severance and Change in Control Benefits
Under each named executive officer’s employment agreement (other than Mr. Trifunovich’s), the Company’s obligations to provide the executive with the severance benefits described above are contingent on:
• The executive’s delivering a signed waiver and release of all claims he may have against the Company and his not revoking such release;
• The executive’s compliance with certain covenants with respect to confidential information and invention assignment; and
• The executive’s compliance with a 12 month non-competition covenant; provided that under the employment agreements for Messrs. Garces and Bellano the non-competition period is reduced to six months in the case of termination without cause or resignation for good reason.
Long Term Incentive Plans
The Company’s long term incentive plans provide for deemed satisfaction of performance goals and accelerated vesting in the event of a change of control of the Company during a performance period as follows. With respect to Long Term Incentive Plan No. 1, which covered the period2004-2006, all named executive officers would have been deemed to have immediately earned the maximum payout due for all long term incentive awards granted to such named executive officer in connection with any change of control. With respect to Long Term Incentive Plan No. 2 and Long Term Incentive Plan No. 3, in connection with a change of control Mr. Conroy and Mr. Arora would be deemed to have immediately earned the maximum payout due for all long term incentive awards granted to him and the other named executive officers would be deemed to have immediately earned 50% of the maximum payout due for all long term incentive awards granted to such named executive officer, unless the change of control is an acquisition or merger for less than $200 million in total value, in which case all performance goals would be deemed satisfied only to the extent the performance targets are satisfied as of the date of the change of control after taking into account on a straight-line basis the shortened time period within which to achieve such performance goals. With respect to Long Term Incentive Plan No. 4, in connection with a change of control all the named executive officers would be deemed to have immediately earned a payout under the plan as follows: (1) if the change in control is an acquisition or merger for more than $400 million in total value, the named executive officers would be deemed to earn the maximum payout; (2) if the change in control is an acquisition or merger for between $300 and $400 million in total value, the named executive officers would be deemed to earn 75% of the maximum payout due; (3) if the change in control is an acquisition or merger for between $200 and $300 million in total value, the named executive officers would be deemed to earn 50% of the maximum payout due; and (4) if the change in control is an acquisition or merger for less than $200 million in total value, all performance goals would be deemed satisfied only to the extent the performance targets are satisfied as of the date of the change of control after taking into account on a straight-line basis the shortened time period within which to achieve such performance goals.
The Company’s long term incentive plans also provide for the payment of prorated awards to participants who die, retire or become disabled during the performance period based upon the Company’s performance during the performance period.


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Stock Option Awards
All of the stock option agreements evidencing awards issued to Messrs. Conroy, Arora and Trifunovich contain a change of control provision that provides that in the event of a change of control 50% of all unvested options would become vested upon the change of control and the remaining 50% of unvested options would become vested upon the earlier of six months from the change of control or upon the optionee’s termination without cause occurring prior to such date. The stock option agreements evidencing the June 2006 awards issued to Messrs. Garces and Bellano contain this same provision.
Estimated Post-Employment Compensation and Benefits
The following table sets forth the estimated post-employment compensation and benefits that would have been payable to Mr. Conroy under his employment agreement and the Company’s long term incentive plans, assuming that each covered circumstance under such arrangements occurred on December 31, 2006.
                     
  Severance
             
  Eligible
  Severance
        Any Other
 
  Termination
  Eligible
        Reason,
 
  and No Change
  Termination
     Termination
  including
 
  of Control
  and Change of
  Change of
  for Death,
  Voluntary
 
  Within 12
  Control Within
  Control (No
  Retirement or
  Termination
 
Benefits and Payments
 Months **  12 Months **  Termination)  Disability  or For Cause 
 
Severance Pay  562,500(1)  750,000(2)         
Incentive Plan Award(3)  281,250   281,250          
Long-Term Incentive Plans  1,500,000(4)  4,125,000(5)  4,125,000(5)  1,500,000(4)   
Unvested Stock Options(6)  249,600   499,200   499,200       
Health and Dental Insurance(7)  12,924   12,924          
Outplacement Consulting(8)  10,000   10,000          
TaxGross-Up(9)
     2,514,235   2,514,235       
Total:  2,616,274   8,192,609   7,138,435   1,500,000    
**“Severance Eligible Termination” means the executive’s termination by the Company without cause or by the executive for good reason.
(1)Represents 18 months severance.
(2)Represents 24 months severance.
(3)Represents 2006 annual incentive award.
(4)Represents amounts payable under Long Term Incentive Plans based on: (i) actual performance for LTIP No. 1 performance period(2004-2006) and (ii) assuming target level performance for LTIP Nos. 2 and 3 (which have performance periods of2005-2007 and2006-2008, respectively).
(5)Assumes the change of control involves an acquisition or merger for more than $200 million in total value.
(6)Represents the value of unvested options held on December 31, 2006 accelerated in connection with termination, based upon the amount by which the closing market price ($4.81) of the underlying shares of common stock on such date exceeded the exercise price.
(7)Represents the cost of paying for premiums for healthand/or dental in the event that Mr. Conroy elects COBRA coverage for the maximum of 12 months.
(8)Reflects the maximum amount of outplacement services required to be provided.
(9)Reflects estimated taxgross-up payment.


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The following table sets forth the estimated post-employment compensation and benefits that would have been payable to Mr. Arora under his employment agreement and the Company’s long term incentive plans, assuming that each covered circumstance under such arrangements occurred on December 31, 2006.
                     
     Severance
          
     Eligible
          
  Severance
  Termination
          
  Eligible
  and Change of
        Any Other
 
  Termination
  Control Within
        Reason,
 
  and No Change
  6 Months
     Termination
  including
 
  of Control
  Before or 12
  Change of
  for Death,
  Voluntary
 
  Within 12
  Months After
  Control (No
  Retirement or
  Termination
 
Benefits and Payments
 Months **  **  Termination)  Disability  or For Cause 
 
Severance Pay  265,000(1)  265,000(1)         
Incentive Plan Award(2)  159,000   159,000          
Long-Term Incentive Plans     2,472,000   2,472,000(3)  901,333(4)   
Unvested Stock Options(5)     224,379   224,379       
Health and Dental Insurance(6)  12,924   12,924          
Outplacement Consulting(7)  10,000   10,000          
Total:  446,924   3,143,303   2,696,379   901,333    
**“Severance Eligible Termination” means the executive’s termination by the Company without cause or by the executive for good reason.
(1)Represents 12 months severance.
(2)Represents 2006 annual incentive award.
(3)Assumes the change of control involves an acquisition or merger for more than $200 million in total value.
(4)Represents amounts payable under Long Term Incentive Plans based on: (1) actual performance for LTIP No. 1 performance period(2004-2006) and (2) assuming target level performance for LTIP Nos. 2 and 3 (which have performance periods of2005-2007 and2006-2008, respectively).
(5)Represents the value of unvested options held on December 31, 2006 accelerated in connection with change of control, based upon the amount by which the closing market price ($4.81) of the underlying shares of common stock on such date exceeded the exercise price.
(6)Represents the cost of paying for premiums for healthand/or dental in the event that Mr. Arora elects COBRA coverage for the maximum of 12 months.
(7)Reflects the maximum amount of outplacement services required to be provided.


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The following table sets forth the estimated post-employment compensation and benefits that would have been payable to Messrs. Trifunovich, Garces and Bellano under Mr. Trifunovich’s offer letter and Messrs. Garces’ and Bellano’s employment agreements described above and the Company’s long term incentive plans, assuming that each covered circumstance under such arrangements occurred on December 31, 2006 (and for purposes of determining severance pay that Messrs. Garces’ and Bellano’s agreements had been entered into prior to such date).
                     
     Severance
          
     Eligible
          
  Severance
  Termination
          
  Eligible
  and Change
          
  Termination
  of Control
        Any Other
 
  and No
  Within 6
        Reason,
 
  Change of
  Months
     Termination
  including
 
  Control
  Before or 12
  Change of
  for Death,
  Voluntary
 
  Within 12
  Months After
  Control (No
  Retirement or
  Termination
 
Benefits and Payments
 Months **  **  Termination)  Disability  or For Cause 
 
Ivan Trifunovich:                    
Severance Pay  265,000(1)  265,000(1)         
Incentive Plan Award(3)  139,125   139,125          
Long-Term Incentive Plans        1,576,750(4)  680,167(5)   
Unvested Stock Options(7)     96,385   96,385   0    
Total:  404,125   500,510   1,673,135   680,167    
Jorge Garces:                    
Severance Pay  92,500(2)  185,000(1)         
Incentive Plan Award(3)  97,125   97,125          
Long-Term Incentive Plans        582,750(4)  388,500(5)   
Health and Dental Insurance(6)  6,462   6,462          
Unvested Stock & Options(7)     59,907   59,907   0    
Total:  196,087   348,494   642,657   388,500    
John Bellano:                    
Severance Pay  87,500(2)  175,000(1)         
Incentive Plan Award(3)  105,000   105,000          
Long-Term Incentive Plans        630,000(4)  420,000(5)   
Health and Dental Insurance(6)  9,126   9,126          
Unvested Stock & Options(7)     153,457   153,457   0    
Total:  201,626   429,458   783,457   420,000    
**“Severance Eligible Termination” means the executive’s termination by the Company without cause or by the executive for good reason.
(1)Represents 12 months severance.
(2)Represents six months severance.
(3)Represents 2006 annual incentive award.
(4)Assumes the change of control involves an acquisition or merger for more than $200 million in total value.
(5)Represents amounts payable under Long Term Incentive Plans based on: (1) actual performance for LTIP No. 1 performance period(2004-2006) and (2) assuming target level performance for LTIP Nos. 2 and 3 (which have performance periods of2005-2007 and2006-2008, respectively).
(6)Represents the cost of paying for premiums for health and/or dental in the event that Messrs. Garces and Bellano elect COBRA coverage for the maximum of 6 months.
(7)Represents the value of unvested options and restricted stock units held on December 31, 2006 accelerated in connection with change of control, based upon the amount by which the closing market price ($4.81) of the underlying shares of common stock on such date exceeded the exercise price.


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Equity Compensation Plan Information
The following table summarizes the number of outstanding options granted to employees, directors Lloyd Smith, Ph.D. Tom Daniel John Neis EXECUTIVE OFFICERS OF THE COMPANY and consultants, as well as the number of securities remaining available for future issuance, under our compensation plans as of December 31, 2006.
             
        Number of
 
        securities
 
        remaining available
 
        for future issuance
 
  Number of securities
  Weighted average
  under equity
 
  to be issued upon
  exercise price
  compensation plans
 
  exercise of out-
  of outstanding
  (excluding securities
 
  standing options,
  option warrants
  reflected in the
 
Plan Category
 warrants and rights  and rights  first column) 
 
Equity compensation plans approved by security holders
            
Incentive Stock Plans  7,896,686  $4.06   2,569,563 
Employee Stock Purchase Plan  Not Applicable(1)  Not Applicable(1)  306,367 
Total  7,896,686  $4.06   2,875,930 
Equity compensation plans not approved by security holders
            
             
None  0   0   0 
             
Net Total
  7,896,686  $4.06   2,875,930 
(1)We maintain an Employee Stock Purchase Plan that permits employees to have payroll deductions made to purchase shares of Common Stock during specified purchase periods. The purchase price is the lower of 85% of (1) the fair market value per share of Common Stock on the first business day of the purchase period and (2) the fair market value per share of Common Stock on the last business day of the purchase period. Consequently, the price at which shares will be purchased for the purchase period currently in effect and future purchase periods is not known.
Executive Officers of the Company
The executive officers of the Company as of April 29, 2004 are set forth below: Lance Fors, Ph.D. (46)
Kevin Conroy (41), our founder and Chairman of the Board, has served as our President and Chief Executive Officer and as one of our directors since our inceptionDecember 2005. Mr. Conroy joined Third Wave as Vice President of Legal Affairs in 1993. Dr. ForsJuly 2004 and served as our PresidentGeneral Counsel from 1993 until 2003. Dr. Fors receivedOctober 2004 to December 2005. Prior to joining Third Wave, Mr. Conroy worked for GE Healthcare, where he oversaw the development and management of its information technologies group intellectual property portfolio, and developed and executed litigation, licensing, and corporate product acquisition legal strategies. Before joining GE, Mr. Conroy was Chief Operating Officer of two early stage venture-based technology companies in Northern California. Prior to those positions, he was an intellectual property litigator at two Chicago law firms, McDermott Will & Emery, and Pattishall, McAuliffe, Newbury, Hilliard and Geraldson, where he was a partner. He earned his Ph.D.B.A. in molecular biologyelectrical engineering at Michigan State University and his J.D. from the California InstituteUniversity of TechnologyMichigan.
Maneesh Arora (38), joined Third Wave in 1990. Dr. Fors has over twenty yearsJanuary 2003 with a strong background in finance and business strategy. He joined the company as Director of researchStrategy and development experiencewas promoted successively to Vice President and is the inventor on 21 issued and pending patents in the area of DNA and RNA sequence analysis. John J. Puisis (44) has served as our Senior Vice President since September 2001. Mr. Puisis also served as ourin 2004. He was appointed Chief Financial Officer from September 2001 until October 2003. In January 2003, Mr. Puisis was also assigned the title and duties of Chief Operating Officer and in October of 2003, he was assigned the title and duties of President. From 1996 until he joined the Company, Mr. Puisis held senior management positions at the Spencer Stuart and Egon Zehnder executive recruitment firms, specializing in recruiting for the biotechnology and pharmaceutical industries. From 1989 to 1996, Mr. Puisis held key financial executive positions at DEKALB Genetics and Kraft Foods. Prior to 1989, Mr. Puisis held various positions at several large public accounting firms. Mr. Puisis received an M.B.A. from Northwestern University and a B.A. in accounting from Northern Illinois University. He is a certified public accountant. Maneesh Arora, (35) joined us in January 2003 as Director of Marketing. In October 2003, Mr. Arora was promoted to Vice President of Marketing and Strategy and in March 2004 he was promoted to Senior Vice President.2006. Prior to joining us,Third Wave, Mr. Arora was Director of Corporate Strategy and New Ventures for Ondeo Nalco. Prior to that he spent nine yearsNalco Chemical Company. Mr. Arora began his career at Kraft Foods inas a variety of rolesfinancial analyst and held several positions of increasing responsibility during his nine years there. He earned a bachelor’s degree in marketingeconomics from the University of Chicago and sales. Mr. Arora received hisan M.B.A. in marketing, management and strategy from the Kellogg Graduate School of Management and his B.A. in economics from the University of Chicago. David Nuti (44) joined the Company in April 2002 as Corporate Controller and assumed the roles of Vice President of Operations and Chief Financial Officer in 2003. Prior to joining the Company in 2002, Mr. Nuti was Vice President and Corporate Controller of Fiskars Brands from 2000 to 2002. From 1991 to 1999, Mr. Nuti held positions at Rubbermaid Inc., including Vice President of Finance and Vice President of Operations. Mr. Nuti received his B.S. in business administration from Northern Illinois University and an M.B.A. from Lewis University. Management.
Ivan D. Trifunovich, Ph.D. (40)(43), joined us as Senior Vice President and General Manager of our Genomics business unit in December 2001. From 1999 until joining us, Dr. Trifunovich was, successively, 12 previously held successive positions as Vice President ofe-Business and Vice President of Research Strategy and


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Operations at Pharmacia Corp. Prior to 1999,joining Pharmacia, Dr. Trifunovich was a Director of New Product Marketing at Johnson & Johnson, Inc. From 1992 to 1997, Dr. Trifunovich held various positionsHe began his career at Bristol-Meyers Squibb, Inc. as a bench scientist, where he held several positions of increasing responsibility. Dr. Trifunovich received his Ph.D. in organic chemistry at UCLA and hisan M.B.A. at the University of Pennsylvania'sPennsylvania’s Wharton School of Business. He is the holder of ten10 U.S. patents. John Comerford (41) joined us in September 2000 as Vice President, General Counsel and Secretary. From 1998 until joining us, Mr. Comerford was Corporate General Counsel and Secretary at Lunar Corporation, a medical device company. From 1990 to 1997, Mr. Comerford was Associate Resident Counsel at National Presto Industries, Inc. Prior to 1990, Mr. Comerford was a Staff Attorney at Fort Howard Corporation. Mr. Comerford received a J.D. from Marquette University and a B.A. in business administration from St. Norbert College. Jacob Orville (30)
Cindy S. Ahn (34), joined us in April 20022006 as Vice President, Legal and General Counsel. In August 2006, Ms. Ahn was appointed Corporate Secretary. Prior to joining Third Wave, Ms. Ahn was a partner at Kirkland & Ellis LLP where she focused on intellectual property litigation, more specifically, patent litigation. Prior to Kirkland & Ellis, Ms. Ahn also practiced in the intellectual boutique firm Finnegan, Henderson, Farabow, Garrett & Dunner in Washington, D.C. Ms. Ahn earned her B.S. in biology at University of Illinois at Urbana-Champaign and her J.D., cum laude, at the Washington College of Law at American University in Washington, D.C.
John Bellano (38), joined us in February 2005 as Regional Vice President of Sales from Roche Diagnostics. He was promoted to Vice President, Sales in January 2006. Mr. Bellano joined Roche in early 2000, where he became one of four regional business managers for its molecular business in the United States. As a regional business manager, he hired and developed a sales team of 11 representatives with revenues of more than $50 million. His sales organization regularly exceeded its goals. Mr. Bellano has also managed multi-million dollar territories for Abbott Laboratories and Sanofi Diagnostics Pasteur, where he was responsible for infectious disease products in the northeastern United States.
Jorge A. Garces (35), has served as our Vice President, Research and Development since October 2006. Mr. Garces joined us in October 2005 as Executive Director of Clinical Development and was Vice President of Product and Platform Development from April 2006 through October 2006. Prior to joining Third Wave, Dr. Garces served as Director of Clinical SalesMolecular R&D at Genzyme Genetics, where he oversaw the technology and assumedproduct development activities of laboratory staff in New York, Los Angeles, and Westborough, MA. Before joining Genzyme, Dr. Garces worked as an associate product manager and R&D scientist at Athena Diagnostics and served as a database curator for Proteome, Inc. He earned his B.A. in biology from Brooklyn College and his Ph.D. in Cell and Molecular Biology from the roleCity University of New York. Dr. Garces completed his post-doctoral training at the University of Massachusetts Medical School.
Greg Hamilton (37), has served as our Vice President, Finance and Operations since October 2006. Mr. Hamilton joined us in February 2005 as Executive Director, Planning and Administration and served as Vice President of Global Sales in September 2003.Finance from January 2006 through October 2006. Mr. Hamilton joined the Company from Leo Burnett USA, where he served first as controller of its U.S. subsidiaries and then successively as vice president and chief financial officer of three of its business units. Prior to joining us,Leo Burnett USA, Mr. Orville held salesHamilton was an auditor and management positions with Smiths Medical. Mr. Orville received his B.A.consultant at the Arthur Andersen and Accenture firms. He earned an M.B.A. from the University of Massachusetts. Chicago’s Graduate School of Business and a bachelor’s degree in finance from Purdue University.
REPORT OF THE AUDIT COMMITTEE
The audit committee oversees the Company'sCompany’s financial reporting process on behalf of the board of directors. The audit committee is governed by a written charter approved by the board of directors. Management has the primary responsibility for the financial statements and the reporting process including the systems of internal controls. In fulfilling its oversight responsibilities, the audit committee reviewed with management the audited financial statements in the Company'sCompany’s Annual Report onForm 10-K, the unaudited financial statements in Quarterly Reports onForm 10-Q, and financial result press releases with management including a discussion of the quality, not just the acceptability, of the accounting principles, the reasonableness of significant judgments, and the clarity of disclosures in the financial statements.
The audit committee reviewed with the independent auditors, who are responsible for expressing an opinion on the conformity of those audited financial statements with accounting principles generally accepted in the United States, their judgments as to the quality, not just the acceptability, of the Company'sCompany’s accounting principles and such other matters as are required to be discussed with the audit committee under auditing standards generally accepted in the United States. In addition, the audit committee has discussed with the independent auditors the matters required to be discussed by Statement on Auditing Standards No. 61, as amended, and the audit committee has


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discussed with the independent auditors the auditors'auditors’ independence from management and the Company including the matters in the written disclosures required by the Independence Standards Board Standard No. 1 and considered the compatibility of non-audit services with the auditors'auditors’ independence.
The audit committee discussed with the Company'sCompany’s independent auditors the overall scope and plans for their audit. The audit committee meets with the independent auditors, with and without management present, to discuss the results of their examinations, their evaluations of the Company'sCompany’s internal controls, and the overall quality of the Company'sCompany’s financial reporting. The audit committee held six8 meetings in 2003. 2006.
In reliance on the reviews and discussions referred to above, the audit committee recommended to the board of directors (and the board hasof directors approved) that the audited financial statements be included in the Company's Annual Report on Form 10-K for the year ended December 31, 2003. The audit committee and2006 be included in the board have also recommended the selection of the Company's independent auditors. 13 The foregoing report shall not be "soliciting material" or to be "filed" with the Securities and Exchange Commission, nor shallCompany’s Annual Report onForm 10-K for such information be incorporated by reference into any future filing under this Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, except to the extent the Company specifically incorporates it by reference into such filing. year.
Respectfully submitted,
The audit committee of the board of directors John Neis G. Steven Burrill Tom Daniel
Lionel Sterling
James Connelly
Lawrence Murphy
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS,
DIRECTORS AND MANAGEMENT
The following table shows information known to us with respect to the beneficial ownership of our common stock as of February 14, 2004,April 30, 2007 by: - each person (or group of affiliated persons) who owns beneficially 5% or more of our common stock; - each of our directors; - each of the Named Executive Officers; and - all of our directors and executive officers as a group.
• each person (or group of affiliated persons) who owns beneficially 5% or more of our common stock;
• each of our directors;
• each of the Named Executive Officers; and
• all of our directors and executive officers as a group.


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Except as indicated in the footnotes to this table and subject to community property laws where applicable, the persons named in the table have sole voting and investment power with respect to all shares of our common stock shown as beneficially owned by them. Beneficial ownership and percentage ownership are determined in accordance with the rules of the Securities and Exchange Commission. Addresses for those 14 individuals for which an addressThe percentage ownership is notbased on 42,221,561 shares of common stock outstanding as of April 30, 2007. Each share of common stock outstanding on the record date is entitled to one vote on each matter considered at the 2007 Annual Meeting. Unless otherwise indicated, is:the address for each of the individuals listed below is c/o Third Wave Technologies, Inc., 502 South Rosa Road, Madison, Wisconsin 53719.
             
  Amount and Nature of Beneficial Ownership 
     Shares Subject to
    
Name of Beneficial Owner
 Total Number(1)  Options  Percentage 
 
Gordon F. Brunner  77,500   45,000   * 
James Connelly  287,500   10,000   * 
Kevin T. Conroy  297,432   280,000   * 
Lawrence Murphy  35,000   15,000   * 
Katherine Napier  17,100   15,000   * 
Lionel Sterling  36,000   15,000   * 
David A. Thompson  134,300   75,900   * 
Maneesh Arora  428,870   407,499   * 
Ivan Trifunovich  405,963   379,000   * 
Jorge Garces  24,578   23,778   * 
John Bellano  27,794   26,666   * 
All directors and executive officers as a group (13 persons)  1,831,989   1,335,759   2.9%
State of Wisconsin Investment Board  4,399,000(2)     10.5%
Deerfield Group  4,934,065(3)     11.8%
SHARES BENEFICIALLY OWNED --------------------------------------------- SHARES SUBJECT TO BENEFICIAL OWNER TOTAL NUMBER OPTIONS PERCENTAGE - ---------------- ------------ ----------------- ---------- 5% SHAREHOLDERS:
indicates less than 1%
(1)Includes shares currently owned and shares subject to options which are exercisable within 60 days.
(2)Information is as of December 31, 2006 and based on a Schedule 13G filed with the Securities and Exchange Commission by the State of Wisconsin Investment Board(1)................. 5,523,000 0 13.88% MazamaBoard (“SWIB”). The address of SWIB is P.O. Box 7842, Madison, Wisconsin 53707.
(3)Information is as of December 31, 2006 and based on a Schedule 13G filed with the Securities and Exchange Commission by Deerfield Partners, L.P. (“Partners”), a Delaware limited partnership, Deerfield Capital, L.P., a Delaware limited partnership (“Capital”), Deerfield International Limited, a British Virgin Islands corporation (“International”), Deerfield Special Situations Fund, L.P., a Delaware limited partnership (“Special”), Deerfield Management Inc.(2)..................... 3,639,484 0 9.17% BankCompany, L.P., a New York limited partnership (“Management”), Deerfield Special Situations Fund International Limited, a British Virgin Islands corporation (“Situations”), and James E. Flynn (“Flynn”). The address of America Corporation(3)......................... 2,503,050 0 6.40% NAMED EXECUTIVE OFFICERS AND DIRECTORS: Lance Fors, Ph.D.(4)................................... 2,448,759 537,959 6.01% John Puisis............................................ 278,073 243,750 * Lloyd M. Smith, Ph.D.(5)............................... 2,054,500 27,700 5.11% John Neis(6)........................................... 1,848,025 27,700 4.60% David A. Thompson...................................... 70,900 70,900 * Tom Daniel(7).......................................... 1,349,326 27,700 3.36% G. Steven Burrill(8)................................... 1,058,563 27,700 2.63% Kenneth R. McGuire..................................... 2,531,200 27,700 6.30% Gordon F. Brunner...................................... 18,500 7,500 * Sam Eletr.............................................. 7,500 7,500 * Maneesh Arora.......................................... 60,156 56,250 * Ivan Trifunovich....................................... 130,000 130,000 * John Comerford......................................... 142,871 113,300 * David Nuti............................................. 63,125 37,500 * Jacob Orville.......................................... 44,379 35,000 * All directorsPartners, Capital, Special, Management and executive officers as a group (15 persons)............................................. 12,105,877 1,378,159 * Flynn is 780 Third Avenue, 37th Floor, New York, New York 10017. The address of International and Situations is c/o Bisys Management, Bison Court, Columbus Center, P.O. Box 3460, Road Town, Tortola, British Virgin Islands.
- --------------- * indicates less than 1% (1) Based on information provided in the Schedule 13G filed by the State of Wisconsin Investment Board ("SWIB") with the Securities and Exchange Commission on February 11, 2004. The address of SWIB is P.O. Box 7842, Madison, Wisconsin 53707. (2) Based on information provided in Schedule 13G filed by Mazama Capital Management, Inc. ("MCM") with the Securities and Exchange Commission on February 11, 2004. The Schedule 13G reports that MCM has sole voting power with respect to 1,870,500 of those shares and sole dispositive power with respect to 3,639,484 of those shares. It does not indicate who has voting power with respect to the remaining 1,764,434 shares. The address of MCM is One S.W. Columbia, Suite 1860, Portland, Oregon 97258. (3) Based on information provided in the Schedule 13G filed by Bank of America Corporation ("BAC"), NB Holdings Corporation ("NBH"), Bank of America, N.A. ("BA"), BANA #1 LLC ("BANA") and Bank of America Strategic Solutions, Inc. ("BASS") with the Securities and Exchange Commission on February 17, 2004. The Schedule 13G reports that each of BAC, NBH, BA and BANA have shared voting and dispositive power with respect to all 2,503,050 shares. (4) Includes 1,900,800 shares of common stock held in a voting trust for the benefit of Dr. Fors' family members. Dr. Fors and his wife, Charlotte H. Selover, are co-trustees of this voting trust. (5) Includes 148,800 shares of common stock held in a voting trust for the benefit of Dr. Smith's family members. Dr. Smith is the sole trustee of this voting trust. 15 (6) Includes 369,787 shares held by Venture Investors of Wisconsin; 269,400 shares held by Venture Investors Early Stage II Limited Partnership; 170,400 shares held by Venture Investors Early Stage Fund III Limited Partnership. (7) Includes 774,312 shares owned by Schroder Ventures International Life Sciences Fund II LPI; 329,524 shares held by Schroder Ventures International Life Sciences Fund II LPII; 88,630 shares held by Schroder Ventures International Life Sciences Fund II LPIII; 22,282 shares held by Schroder Ventures International Life Sciences Fund Group Co-Investments Scheme; 11,842 shares held by Schroder Ventures International Life Sciences Fund II Strategic Partners LP; and 25,200 shares held by Schroder Ventures Investments Limited. Mr. Daniel is a manager of a company that provides consulting services to Schroder Ventures funds. Mr. Daniel disclaims beneficial ownership of the shares held by the various Schroder Venture funds. The address of Schroder Ventures International Life Sciences Fund II, LPI, Schroder Ventures International Life Sciences Fund II LPII, and Schroder Ventures International Life Sciences Fund II LPIII is 875 Third Avenue, 22nd Floor, New York, NY 10022-6225. The address of Schroder Ventures Co-Investment Scheme is 22 Church Street, Hamilton HM 11, Bermuda. The address of Schroder Ventures Investments Limited is P.O. Box 255, Barfield House, St. Julian's Avenue, St. Peter Port, Guernsey GY1 4ND Channel Islands, United Kingdom. (8) Includes 1,020,863 shares held by the Burrill Agbio Capital Fund, LP. Mr. Burrill is general partner of Burrill Agbio Capital Fund, LP and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest in these shares.
SECTION 16(A)16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
Section 16(a) of the Securities Exchange Act of 1934 requires our directors and executive officers, and any persons who beneficially own more than ten percent of our common stock, to file with the Securities and Exchange Commission initial reports of ownership and reports of changes in ownership of common stock. To our knowledge, based solely on review of the copies of such reports sent to us and written representations that no other reports were required, we believe that during the year ended December 31, 2003,2006, our directors, officers and ten percent shareholdersten-percent stockholders complied with their Section 16(a) filing requirements, except that Katherine Napier filed a change in beneficial ownership of Lance Fors waslate Form 3 and Gordon Brunner filed late. one late Form 4 reporting one transaction.


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CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS In December
Pursuant to its charter, the audit committee is responsible for reviewing related person transactions for potential conflicts of 2003,interest. The audit committee has adopted a written policy setting forth the stepson of Dr. Fors, who had been an employee ofprocedures and standards the Company for more than six years, was terminated duecommittee will apply to a position elimination.reviewing and approving related person transactions. The terminated employee was provided with a severance package. The terms of the severance package were reviewed and approved by the compensation committee and were foundpolicy covers any transaction that is required to be consistent with severance packages offered to similarly affected employees in comparable positions with equivalent terms of employment. 16 SHAREHOLDER RETURN PERFORMANCE GRAPH The following graph compares the percentage change in the cumulative return on our common stock against the NASDAQ Stock Market U.S. Index (the "NASDAQ Index") and a peer group composed of the companies listed below (the "Peer Group"). The graph assumes a $100 investment on February 9, 2001 (the date of our initial public offering) in each of our common stock, the NASDAQ Index and the Peer Group and assumes that all dividends, if paid, were reinvested. This table does not forecast future performance of our common stock. (PERFORMANCE GRAPH)
- --------------------------------------------------------------------------------------------------------------------------- 2/9/01 3/31/01 6/30/01 9/30/01 12/31/01 3/31/02 6/30/02 9/30/02 12/31/02 3/31/03 - --------------------------------------------------------------------------------------------------------------------------- TWTI 100.00 63.64 93.91 57.45 66.82 30.45 20.36 12.27 24.45 29.82 NASDAQ 100.00 74.48 87.44 60.66 78.93 74.68 59.22 47.43 54.05 54.28 Former Peer Group 100.00 53.57 65.66 37.12 62.54 39.95 28.59 19.00 19.20 18.77 Current Peer Group 100.00 86.60 132.47 91.84 112.48 118.85 105.97 91.23 111.79 102.42 - --------------------- ---------------------------- 6/30/03 9/30/03 12/31/03 - --------------------- ---------------------------- TWTI 41.09 29.36 41.36 NASDAQ 65.67 72.32 81.08 Former Peer Group 24.57 28.32 42.19 Current Peer Group 165.11 201.95 234.39
The former Peer Group consists of the following companies: Applera Corporation, Orchid Biosciences, Inc., Sequenom, Inc., Affymetrix, Inc. and Nanogen, Inc. The current Peer Group consists of the following companies: Celera Diagnostics, LLC, Ventana Medical Systems, Digene, Bio-Rad Laboratories. This change in peer group was made to better reflect the Company focus on molecular diagnostics businesses. The foregoing graph and accompanying material shall not be "soliciting material" or to be "filed" with thereported by applicable Securities and Exchange Commission nor shallrules and any other transaction, arrangement or relationship (including any indebtedness or guarantee of indebtedness), or any series of similar transactions, arrangements or relationships, (1) in which the Company (including any of its subsidiaries) was, is or will be a participant, (2) the amount involved exceeds $120,000 and (3) in which any Related Person had, has or will have a direct or indirect interest. Under the policy, “Related Person” means: (1) any person who is, or at any time since the beginning of the Company’s last fiscal year was, a director or executive officer of the Company or a nominee to become a director of the Company; (2) any person who is known to the Company to be the beneficial owner of more than 5% of any class of the Company’s voting securities; (3) any immediate family member of any of the foregoing persons, and (4) any firm, corporation or other entity with which any of the foregoing persons is employed or is a partner or principal or holds a similar position or in which such person has, together with other such persons, a 10% or greater beneficial ownership interest. Under the policy the audit committee will approve a Related Person transaction only if it determines that the transaction is in, or is not inconsistent with, the best interests of the Company and its stockholders. In determining whether to approve or ratify a Related Person transaction, the audit committee takes into account, among other factors it deems appropriate, the benefits to the Company; the impact on a director’s independence in the event the Related Person is a director, an immediate family member of a director or an entity in which a director is a partner, stockholder or executive officer; the availability of other sources for comparable products or services; the terms of the transaction; and the terms available to unrelated third parties or to employees generally. In addition, the policy requires that notice be provided to the audit committee of transactions involving less than $120,000 but that would otherwise be Related Person transactions covered by the scope of the policy.
We were not party to any reportable related person transactions in 2006.
CODE OF BUSINESS CONDUCT
We have adopted a Code of Business Conduct (the “Code of Business Conduct”) which applies to all directors, officers and employees. A copy of the Code of Business Conduct is available on our website atwww.twt.com.  We intend to make any disclosures regarding amendments to, or waivers from, the Code of Business Conduct required underForm 8-K by posting such information be incorporated by reference into any future filing under this Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, except to the extent the Company specifically incorporates it by reference into such filing. on our website.
OTHER MATTERS
We know of no other matters to be submitted to the shareholdersstockholders at the meeting. If any other matters properly come before the shareholdersstockholders at the meeting, it is the intention of the persons named in the enclosed form of proxy towill vote the shares they represent as the board of directors may recommend. in their discretion.
By Order of the Board of Directors, /s/ JOHN COMERFORD John Comerford
-s- KEVIN T. CONROY
Kevin T. Conroy
President and Chief Executive Officer
Dated: April 29, 2004 17 THIRD WAVE TECHNOLOGIES, INC. June 4, 2007


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THIS PROXY IS SOLICITED BY THE BOARD OF DIRECTORS OF THIRD WAVE TECHNOLOGIES, INC.
PROXY FOR ANNUAL MEETING OF SHAREHOLDERS STOCKHOLDERS
IF NO CHOICE IS SPECIFIED, THE PROXY WILL BE VOTED "FOR"“FOR” THE DIRECTORSDIRECTOR LISTED BELOW AND 2 BELOW.
     The undersigned shareholderstockholder of Third Wave Technologies, Inc., a Delaware corporation (the "Company"“Company”), hereby acknowledges receipt of the Proxy Statement of the Company dated April 29, 2004June 4, 2007, and hereby appoints David NutiCindy Ahn and John Comerford proxyManeesh Arora, each of them, proxies and attorneyattorneys in fact, with full power of substitution, on behalf and in the name of the undersigned, to represent the undersigned at the Annual Meeting of ShareholdersStockholders of the Company to be held at the offices of the CompanyMG&E Innovation Center at 510 Charmany Drive, Madison, Wisconsin 53719 at 9:00 a.m. local time on Tuesday, June 22, 2004July 24, 2007, and any adjournment or adjournments thereof, and to vote all shares of common stock of the Company that the undersigned would be entitled to vote if the undersigned were present, as follows:
     1. The election of the following personsTo elect as directorsa director of the Company each of the nominees listed below, to serve until their successors shall be duly elected and qualified: for a term expiring at the 2010 Annual Meeting of Stockholders.
NAME OF NOMINEEFOR AGAINST - ---------------------- --- ------- Lance Fors WITHHELD
Kevin T. Conroy[   ][   ]
David A. Thompson[   ][   ] John J. Puisis [ ] [ ]
For, except vote withheld from the following nominee(s):
     2. To ratify the appointment of Ernst & YoungGrant Thornton LLP as independent auditorsregistered public accounting firm of the Company for the fiscal year ending December 31, 2004. [ ] For [ ] Against 2007.
[   ] For[   ] Against[   ] Abstain
     3. InThe undersigned shareholder(s) authorize the individuals designated to vote this proxy, to vote, in their discretion, upon any such other mattersothers (none known at the time of solicitation of this proxy) which may properly come before the meetingAnnual Meeting or any adjournmentsadjournment(s) thereof.
The Board of Directors recommends a vote “FOR” each of the proposals.
MARK HERE FOR ADDRESS CHANGE AND NOTE AT LEFT [   ] Grant Authority [ ] Withhold Authority THIS PROXY WILL BE VOTED IN ACCORDANCE WITH THE SPECIFIC INDICATION ABOVE. IN THE ABSENCE OF SUCH INDICATION, THIS PROXY WILL BE VOTED FOR THE DIRECTORS LISTED ABOVE AND FOR ITEM 2 AND, AS THE PROXYHOLDER DEEMS ADVISABLE, ON ANY OTHER MATTERS WHICH MAY PROPERLY COME BEFORE THE MEETING OR ANY ADJOURNMENTS THEREOF. DATED: _____________________________, 2004 - ------------------------------------- Signature of Shareholder - ------------------------------------- PLEASE PRINT NAME(S) I plan to attend the meeting: [ ] Yes [ ] No Taxpayer Identification No. (or Social Security Number): ------------------------
Sign exactly as your name(s) appear(s) on the stock certificate(s). A corporation is requested to sign its name by its President or other authorized officer, with the office held designated. Executors, administrators, trustees, etc., are requested to so indicate when signing. If a stock is registered in two names, both should sign. SHAREHOLDERS
STOCKHOLDERS SHOULD SIGN THIS PROXY PROMPTLY AND RETURN IT IN THE ENCLOSED ENVELOPE.PLEASEENVELOPE. PLEASE RETURN ALL PAGES OF THIS PROXY
PROXY.
Signature:Date:Signature:Date: